Sponsor or institution
Clinical trials and research at Brown University
As of November 12, 2026, Find a Trial lists 31 clinical trials run by Brown University that are recruiting, at sites in 3 countries (most in United States (29), Angola (1), Colombia (1)). 1 was first registered in the last 30 days. By phase: Phase 2 (7), Phase 1 (2), Phase 3 (2), Phase 1/2 (1). There are also 535 NIH-funded research projects at this institution, with $342.2 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 31Clinical trials
- 535NIH research projects
- 1New in 30 days
- 3Countries
Newest trials
All recruiting trials (31)
-
Mindful Smartphone Use: A Mindfulness-Based Program for Teens with Sleep and Mood Challenges
This study tests Mindwire, a mindfulness-based program, to see if it helps teens with problematic phone use who also have depression or anxiety.
-
Supporting health by reducing alcohol use and strengthening relationships
This project tests a couples-focused program to help adults with unhealthy drinking and their partners see if the approach is acceptable and feasible.
-
Psilocybin and Belief Updating in Healthy Adults (Phase 1)
This phase 1 study tests whether a single dose of psilocybin affects learning and belief updating in healthy adults, compared with a placebo.
-
Short-Term Multi-Fiber Supplement Effects on Gut Health in Healthy Adults
We’re testing whether a standardized multi-fiber supplement affects bowel habits and gut microbiome signals in healthy adults over 10 days.
-
iPAWS: Helping teens manage pain and risky behaviors after wisdom tooth removal
This program tests a short online intervention to help teens and their parents handle post-surgical pain and reduce risky behaviors after wisdom tooth extraction.
-
Path180: a computer-based skills program to help teens reduce alcohol use
This 8-week trial tests Path180, a computer-based skills training, added to usual care for teens 13–19 with alcohol use disorder to see if it improves daily-life coping skills and outcomes.
-
Targeting alcohol-opioid co-use among young adults with a new mobile health tool
A mobile health app is being tested to help young adults reduce drinking and opioid use when they occur together.
-
TLR9-based immunotherapy for peritoneal cancer with ascites
This trial tests ACM-CpG injections into the abdomen to see if it’s safe and can help people with peritoneal metastases or malignant ascites from colorectal or appendiceal cancer.
-
How price, availability, and cues influence marijuana and cigarette use in young adults
This project will see if changing price, availability, and exposure to cues changes how 18- to 25-year-olds who smoke both marijuana and tobacco choose between them.
-
Probenecid to reduce alcohol craving and consumption
This trial will test whether taking daily probenecid (2 g/day) reduces craving and drinking in adults with moderate-to-severe alcohol use disorder.
-
Tailored reduced-intensity treatment for older adults with head and neck cancer
This trial tests whether a lower-intensity, PD-L1-guided chemoimmunotherapy approach followed by radiation helps frail patients aged 65 and older with stage IB–IVA squamous cell head and neck cancer.
-
Online program to increase activity and healthy eating for Latinas
This 12-week online program will test whether it helps adult Latinas move more, eat more fruits and vegetables, and drink fewer sugary beverages.
-
Preventing Dato‑DXd–related mouth sores with dexamethasone mouthwash
This study will see if using an alcohol‑free dexamethasone mouthwash can prevent mouth sores in adults with advanced breast cancer or non‑squamous non‑small cell lung cancer who are receiving datopotumab deruxtecan.
-
Evaluating an app-based program to reduce physician burnout
This study is testing whether a mindfulness app can help doctors feel less burned out compared to those who don't use the app.
-
Visual perceptual training with patterned and natural images
This project will test whether targeted visual training changes how adults (18–60) perceive patterned and natural images and how those changes appear in brain activity.
-
Evaluating smoking cessation using e-cigarettes and nicotine therapy
This study is testing whether using e-cigarettes or nicotine replacement therapy can help people with obesity who smoke quit smoking and manage their weight better.
-
Intervention to improve PrEP use among Black men who have sex with men
This study is testing a new support program to help Black men who have sex with men start and stick with PrEP to prevent HIV.
-
Mindfulness-based program to boost exercise in inactive Latina women
This study tests if a mindfulness program can help inactive Latina women get more active and improve their exercise habits over 18 months.
-
Exploring health choices and wellness in teenagers
This study looks at how health choices and behaviors change in teenagers aged 13 to 16 by using a smartphone app and having discussions to better understand their wellness as they grow up.
-
Using technology to prevent suicide among youth in Colombia
This study is testing a new technology-based program to help reduce suicidal thoughts and behaviors among young people in Colombian schools.
-
Combining Yttrium-90 with Capecitabine and Atezolizumab for Liver Metastases from Colorectal Cancer
This study is testing a new treatment that combines a special type of radiation with two medications to see if it can help people with advanced colorectal cancer that has spread to the liver.
-
Understanding how multitasking practice affects brain function
This study tests if practicing multitasking helps healthy people improve their brain function and ability to handle multiple tasks at once.
-
Home-based nutrition intervention for Latinx families with preschool children
This study is testing a home-based nutrition program to see if it can help low-income Latinx families with preschool children eat healthier.
-
Using intranasal insulin to treat alcohol use disorder
This study is testing if using intranasal insulin can help people with alcohol use disorder by seeing how it affects them when they drink alcohol.
-
Using a smartphone app to track pain and mood changes
This study is testing a smartphone app to track pain and mood changes in people with chronic pain and healthy individuals to see how these factors affect pain over time.
-
Examining how cannabis affects alcohol consumption
This study is testing how different types of cannabis affect drinking habits in heavy drinkers who use cannabis regularly.
-
Using Hydroxyurea to Treat Sickle Cell Anemia in Children in Africa
This study is testing if hydroxyurea can safely help children with sickle cell anemia in Africa feel better and improve their treatment options.
-
Technology-assisted parenting intervention for adolescents in substance use treatment
This study tests a new program that helps parents of teens in substance use treatment learn better parenting skills through technology to see if it can help their kids stay sober after treatment.
-
Neoadjuvant treatment for operable non-small cell lung cancer using low-dose radiation and immunotherapy
This study is testing a new treatment combining low-dose radiation and immunotherapy for patients with early-stage non-small cell lung cancer to see if it helps shrink tumors before surgery.
-
First-line treatment for follicular and marginal zone lymphoma using mosunetuzumab and lenalidomide
This study is testing if a new combination of treatments can help adults with untreated follicular or marginal zone lymphoma feel better and improve their response to therapy.
-
Health effects of electronic cigarettes in smokers living with HIV
This study is testing if using electronic cigarettes can help HIV-positive smokers who aren't ready to quit feel better and change their smoking habits over 12 weeks.
NIH-funded research (newest 40 of 535)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Digital twins of the spleen to help design better therapies for sickle cell disease
A computer-driven replica of the spleen is being developed to speed up creating safer and more effective treatments for people with sickle cell disease.
-
Understanding how heavy drinking and anxiety relate in emerging adults
This grant studies how heavy alcohol use and anxiety symptoms interact in young adults (ages 18–34) and what biological stress markers might reveal about that relationship.
-
Population Studies Center at Brown: research to improve health and well-being of people, including children and those affected by HIV/AIDS
A Brown University center researchers study how social and environmental factors shape health, with a focus on children, families, HIV, and health disparities.
-
Role of ER membrane contact sites in synapse formation and plasticity
A study from Brown University will explore how connections between cell parts help neurons form and adapt synapses, which may shed light on degenerative brain disorders.
-
Public Use Data on Mexican and Central American Immigration (health data project)
A national study will collect and share health survey data from Mexican and Central American immigrants to understand how health changes over time in this population.
-
Impact of Virtual Doula Support on Birth Outcomes in Rural Communities
A study to see if virtual doula support improves birth outcomes for people giving birth in rural areas.
-
New ultra-sensitive brain magnetometer for measuring brain signals in everyday settings
A project to create a highly sensitive, untethered brain-measuring device that can detect tiny brain signals in real-life situations.
-
Technology-assisted suicide prevention for youth in Colombian school settings
A youth-focused program will test a culturally tailored digital platform and teacher training to reduce suicidal thoughts and behaviors in schools.
-
Caspase-8’s key role in helping the lungs tolerate and fight severe infections
This NIH grant studies how a protein called Caspase-8 helps lung immune cells balance fighting infections with protecting lung tissue, aiming to benefit people who get severe pneumonia after flu or other infections.
-
Understanding how brain stimulation and dopamine shape decisions in Parkinson's
A study at Brown University will explore how targeted deep brain stimulation and dopamine levels influence decision making and motivation in people with Parkinson’s disease.
-
Candida albicans in the gut: how it colonizes and affects immune responses
Scientists are studying how the fungus Candida albicans lives in the gut and what allows it to cause infections, with potential implications for preventing disease in people.
-
How pregnancy nutrition and infections shape a baby's early brain
This project looks at whether better maternal nutrition and lower inflammation during pregnancy help fetal brain growth for pregnant women and their unborn babies in low-resource settings.
-
Understanding LINE-1 RNA and how it moves through our cells
This project looks at how the LINE-1 retrotransposon behaves in human cells and how it may affect cancer and other diseases.
-
TAG-MI: A mobile tool to help HIV-positive youth in Ghana stay healthy and keep their care on track
A mobile intervention aims to help young people living with HIV in Ghana stay adherent to ART and attend clinic visits, improving mental health and HIV outcomes.
-
Population modeling to reduce bladder cancer burden
Aimed at predicting and guiding effective, population-based ways to prevent and control bladder cancer.
-
Public data on Mexican and Central American immigration health
A large study will create and use survey data from people in Mexico, El Salvador, Guatemala, Honduras, and the United States to understand how health changes over time among Mexican and Central American immigrants.
-
Public health data on Mexican and Central American immigration and health
A large study will collect and share public health information from migrants in Mexico, Central America, and the U.S. to understand how health changes over time in this population.
-
Public health data on Mexican and Central American immigration health
This grant uses public data to understand how health changes over time among Mexican and Central American immigrants in the U.S. and in home countries.
-
Gene-regulatory steps guiding axon wiring in the spinal cord
A study in mice aims to understand how nerve fibers learn their way during development by looking at how gene activity changes help axons find their targets.
-
Finding immune targets to prevent severe falciparum malaria
Using people’s natural antibody responses to find new vaccine targets that could protect babies and young children from severe falciparum malaria.
-
Green space and its impact on mental health and sleep
A study from Brown University will look at how outdoor greenspace relates to how well kids and adults sleep and feel mentally across different ages.
-
Understanding how phthalates affect male reproductive development and later-life function
This project looks at how everyday chemicals called phthalates may disrupt male reproductive development before birth and affect fertility later in life.
-
Understanding why some young adults have trouble stopping drinking and what happens as a result
This study looks at why some 21-year-olds struggle to limit their drinking and how that affects short- and long-term outcomes.
-
Haplotype linked to malaria drug resistance in Africa
This grant studies a chromosome 7 haplotype in the malaria parasite that may make artemisinin and lumefantrine less effective, with the goal of keeping key treatments working for people in sub-Saharan Africa.
-
Understanding a malaria drug resistance mutation spreading in Africa
A short study will map and characterize a gene change in malaria parasites that may make the standard malaria drugs less effective, focusing on Africa.
-
Noncanonical PARP1 roles in protecting against chromium exposure
This grant studies how PARP1 helps protect people from harmful chromium exposure at work and in the environment by uncovering how chromium-induced DNA damage is repaired.
-
Health Research Core to Boost Rhode Island Clinical and Translational Research
A funding program at Brown University helps Rhode Island researchers gain mentorship, time, and pilot funding to advance patient-centered clinical and community health research.
-
Professional Development Core for clinical and translational research training
A career-development program at Brown University helps Rhode Island researchers build skills, mentorship, and networks to advance patient-centered translational research.
-
Community Engagement and Outreach Core (CEO) for Patient-Centered Research
This grant supports a hub that brings patients, clinicians, and communities together to guide and improve research on chronic disease and access to care in Rhode Island.
-
RDCD Core helps design compliant, data-smart clinical research
A center-level grant to help researchers design and manage high-quality clinical studies with strong data and regulatory support.
-
Administrative Core supports statewide clinical research collaboration
A centralized Administrative Core helps Rhode Island researchers work together more easily and responsibly across institutions.
-
Advance Clinical and Translational Research for Rhode Island Health
A Rhode Island research center is being renewed to speed up real-world health improvements for people in the state and beyond.
-
Understanding Multilevel Drivers of Stimulant Overdose in the US
Researchers will look at how social, health, and supply factors combine to influence stimulant overdose deaths, using data from large populations and conversations with people who use stimulants and the clinicians who care for them.
-
Endothelial KLF4 and heart failure with preserved ejection fraction
A study to understand how a blood-vessel cell regulator called KLF4 might cause heart failure with normal pumping function, with hopes of guiding new treatments.
-
Promoting better glucose control for gestational diabetes with mindfulness during pregnancy
A mindfulness-based program called EMPOWER will be developed and tested to help pregnant women with gestational diabetes manage glucose and improve health for both mom and baby.
-
AL-STEADI: Adapting falls prevention for assisted living communities
A study in assisted living communities will test a tailored program to prevent falls among residents by screening for risk and giving personalized steps to stay safer.
-
Using Virtual Reality to Help Adults with Alcohol Use Disorder Cope in Real-Life Triggers
A VR-based program helps adults with alcohol use disorder learn and practice coping skills in realistic high-risk situations to support abstinence.
-
Wood pellet plants and kids’ health in Mississippi
A study at Brown University will look at how living near wood pellet plants in Mississippi may affect children’s breathing, stress, and overall health.
-
Probenecid for Alcohol Use Disorder
A 12-week study at Brown University will test whether adding probenecid helps people with alcohol use disorder reduce drinking and cravings.
-
Bystander Help in Alcohol-Related Risk Among Young Adults
A study with 18- to 21-year-olds looking at when and how bystanders intervene to reduce harm from peers’ risky drinking.
Quick answers
How many clinical trials run by Brown University are recruiting right now?
31, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (29 trials), Angola (1 trial), Colombia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 7, Phase 1: 2, Phase 3: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.