Short-Term Multi-Fiber Supplement Effects on Gut Health in Healthy Adults
Official title: Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health
Run by Brown University · NCT07787026 · Data updated 2026-11-12
We’re testing whether a standardized multi-fiber supplement affects bowel habits and gut microbiome signals in healthy adults over 10 days.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Brown University Academic / other |
| Locations | 1 site (Providence, Rhode Island) |
| Status | Recruiting |
| Started | August 2026 |
| Main results expected | August 2028 |
| Study ends | August 2029 |
| Registry record updated | August 26, 2026 |
| Trial ID | NCT07787026 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults 18 years or older without chronic disease, not on antibiotics or pre/probiotics in the last 3 months, and without severe dietary restrictions.
✕Probably not a fit
Individuals with chronic health conditions, recent antibiotic/prebiotic/probiotic use, or specific allergies to study ingredients may not experience a benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, parallel-group study compares a multi-fiber supplement to a flavoring control in about 100 healthy adults. Participants will take the assigned product daily for 10 days and report stool frequency and consistency, while researchers analyze microbiome-derived markers related to short-chain fatty acid production. The trial excludes anyone with chronic disease, recent infections, or recent use of antibiotics, probiotics, or prebiotics, to isolate the supplement’s short-term gut effects. The primary goal is to observe early changes in gastrointestinal function and microbial potential related to fiber intake.
Why it matters
Potential benefit: If successful, the study could inform how quick changes in dietary fiber might influence stool patterns and gut microbial activity in healthy individuals.
How similar studies have gone: Previous fiber-related studies have shown measurable short-term gut changes, supporting feasibility of detecting effects in a 10-day timeframe.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * in self-reported good health (i.e. no chronic disease, no acute illness) Exclusion Criteria: * chronic disease * acute illness * antibiotic, or probiotic, or prebiotic use in the prior 3 months * allergies to any of the following: psyllium husk powder, mustard, sesame, soy, tree nuts, pectin, citric acid, wheat, milk, egg, beta-glucan, barley, inulin, agave, resistant maltodextrin, arabinoxylan * adherence to any food-group strict diet (e.g. vegan, vegetarian, keto, etc.) * any of the following groups: adults unable to consent, individuals that are not yet adult, pregnant women, prisoners
Where it's running
-
Biomedical Center
Providence, Rhode Island, United States Recruiting
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.