Condition

Temporomandibular Joint Disorders clinical trials and research

• 17Clinical trials
• 1NIH research projects
• 1New in 30 days
• 20Countries

Newest Temporomandibular Joint Disorders clinical trials

All recruiting trials (17)

• See if low-level laser therapy adds benefit to an occlusal splint for TMD pain

  This study tests whether adding low-level laser therapy to occlusal splint treatment helps reduce pain and improve jaw function for people with temporomandibular disorders.

  Recruiting Future University in Egypt · Cairo · NCT07878247

• Calcium Gluconate-Activated PRP vs. Non-Activated PRP for ADD with Reduction

  This trial tests whether activating PRP with calcium gluconate before a retrodiscal injection helps reduce TMJ pain and improve mouth opening in adults with anterior disc displacement with reduction.

  Recruiting Cairo University · Cairo · NCT07855887

• Body Awareness Therapy to reduce jaw pain and improve jaw function in temporomandibular joint disorder

  This trial will try Body Awareness Therapy in adults with TMD to reduce jaw pain, improve jaw function, and ease stress and anxiety.

  Recruiting Recep Tayyip Erdogan University · Rize · NCT07317570

• Using magnetic stimulation to treat jaw joint disorders

  This study is testing if a special type of magnetic treatment can help people with painful jaw joint disorders feel better when other treatments haven't worked.

  Recruiting University of Coimbra · Coimbra · NCT06813040

• Using light therapy to treat jaw joint issues

  This study is testing whether internal or external light therapy can help people with painful jaw joint issues feel better and improve their jaw function.

  Recruiting University of Alexandria · Alexandria · NCT06763419

• Evaluating balance and social skills in individuals with autism

  This study is testing how balance and social skills are affected in people with autism compared to those without, while also looking at jaw and neck issues.

  Recruiting Kırıkkale University · Kirikkale · NCT06721104

• Comparing high and low molecular weight hyaluronic acid for treating TMJ disorders

  This study is testing whether high or low molecular weight hyaluronic acid injections can help people aged 17 to 70 with TMJ disorders feel better when other treatments haven't worked.

  Recruiting Phase 1/2 Assiut University · Asyut · NCT06694532

• Investigating the link between levonorgestrel intrauterine system and temporomandibular disorders

  This study is trying to see if using a specific birth control device called the levonorgestrel intrauterine system is linked to jaw joint problems in women.

  Recruiting Marmara University · Istanbul, Maltepe · NCT06500390

• Cervical core exercises for treating jaw joint dysfunction

  This study is testing if specific neck exercises can help people with jaw joint pain related to muscle issues feel better over eight weeks.

  Recruiting Istanbul Gelisim University · Istanbul, Avcılar · NCT06222736

• Evaluating a questionnaire for patients with jaw disorders

  This study is testing a new questionnaire to see if it accurately measures how temporomandibular disorders affect people's mental health and quality of life.

  Recruiting at 2 sites Hacettepe University · Karabük, Karabük Province and 1 other locations · NCT06186830

• Characterization of normal and abnormal TMJ movement with real-time MRI

  This study tests a Real Time MRI Rapid Flash sequence to see how the jaw moves in healthy people and people with temporomandibular joint disorders.

  Recruiting Central Hospital, Nancy, France · Nancy · NCT06070558

• Using shock wave therapy to treat jaw pain from muscle disorders

  This study is testing if shock wave therapy can help people with jaw pain from muscle disorders feel better and improve their daily life.

  Recruiting University of Sao Paulo General Hospital · São Paulo, São Paulo · NCT05907239

• Using a smartphone app to track pain and mood changes

  This study is testing a smartphone app to track pain and mood changes in people with chronic pain and healthy individuals to see how these factors affect pain over time.

  Recruiting Brown University · Providence, Rhode Island · NCT05754190

• Validation of a deep learning platform for diagnosing isolated dystonia

  This study is testing a new deep learning tool to see if it can help doctors diagnose isolated dystonia more accurately and quickly.

  Recruiting Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT05317390

• Combining manual therapy and vagus nerve stimulation for jaw pain relief

  This study is testing if combining manual therapy with vagus nerve stimulation can help people with jaw pain feel better and improve their jaw movement.

  Recruiting at 3 sites University of Alcala · Alcalá de Henares, Madrid and 2 other locations · NCT05272488

• Tele-rehabilitation for patients with jaw joint disorders

  This study is testing if remote therapy can help people with jaw joint disorders feel less pain and move their jaws better.

  Recruiting University of Nove de Julho · São Paulo · NCT05006963

• Registry for patients undergoing TMJ replacement

  This study is tracking around 200 patients who are getting a new jaw joint to see how the treatment affects their quality of life and what factors lead to better results over five years.

  Recruiting at 17 sites AO Innovation Translation Center · São Paulo and 22 other locations · NCT03991728

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating brain connectivity in chronic jaw pain disorders

  This study is looking at how the way different parts of the brain connect might affect people with chronic pain from jaw issues, and it hopes to find patterns that could help improve treatment for those dealing with this kind of pain.

  NIH research University of Minnesota · Minneapolis, United States · NIH-10466898

Related topics

Quick answers

How many Temporomandibular Joint Disorders clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in Turkey (Türkiye) (5 trials), Egypt (4 trials), Brazil (3 trials), United States (2 trials), Spain (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →