Characterization of normal and abnormal TMJ movement with real-time MRI
Official title: ChAracterization of Normal and Pathological moRphological Variations of the TEMporomandibular Joint by Real-time magnetIc reSonance Imaging
Run by Central Hospital, Nancy, France · NCT06070558 · Data updated 2026-11-12
This study tests a Real Time MRI Rapid Flash sequence to see how the jaw moves in healthy people and people with temporomandibular joint disorders.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 1 site (Nancy) |
| Status | Recruiting |
| Started | December 12, 2023 |
| Main results expected | December 12, 2026 |
| Study ends | December 12, 2026 |
| Registry record updated | June 17, 2026 |
| Trial ID | NCT06070558 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older who can understand and sign informed consent, are affiliated with a social security scheme, and have no MRI contraindications or extensive metallic dental work.
✕Probably not a fit
Patients with claustrophobia, extensive dental hardware, or contraindications to MRI may not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants will undergo MRI using a Real Time MRI Rapid Flash sequence to characterize both normal and pathological movements of the temporomandibular joint. The study design is observational in nature, focusing on imaging performance and movement characterization rather than a treatment. The assessment aims to determine how well this sequence captures dynamic TMJ motion and distinguishes between healthy and diseased joints. Inclusion is limited to adults able to consent, with MRI compatibility and adequate dentition, while excluding those with MRI contraindications or confounding dental hardware. It is led by CHU de Nancy in France and does not list collaborating centers.
Why it matters
Potential benefit: If successful, the approach could improve understanding of TMJ motion and help guide future diagnostics or imaging protocols.
How similar studies have gone: Imaging-focused investigations of TMJ motion have been explored with dynamic MRI approaches, but real-time rapid flash sequences for this purpose are less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult: age ≥ 18 years old; * Person with the capacity to understand the instructions given; * Person affiliated to a social security scheme or beneficiary of such a scheme; * Person having received complete information on the organization of the Clinical Investigation and having signed informed consent. Exclusion Criteria: * Person with large-scale metallic dental reconstructions; * Edentulism more than 5 teeth; * Claustrophobia; * Contraindication to performing an MRI examination * Persons referred to in Articles 64, 65 and 66 of European Regulation 2017/745 on Medical Devices (RDM) and in L. 1121-5 to L1121-8 of the French Public Health Code
Where it's running
-
CHRU de Nancy
Nancy, France Recruiting
Study contacts
- Study coordinator: Pedro Augusto GONDIM TEIXEIRA, MD, PhD
- Email: p.teixeira@chru-nancy.fr
- Phone: 0033 3 83 85 21 61
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.