Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Using light therapy to treat jaw joint issues

Official title: Internal Photobiomodulation For Management Of Temporomandibular Joint Internal Derangement: A Randomized Clinical Trial

Run by University of Alexandria · NCT06763419 · Data updated 2026-11-12

This study is testing whether internal or external light therapy can help people with painful jaw joint issues feel better and improve their jaw function.

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment50 (estimated)
SponsorUniversity of Alexandria
Academic / other
Locations1 site (Alexandria)
StatusRecruiting
StartedDecember 25, 2024
Main results expectedFebruary 28, 2025
Study endsFebruary 28, 2025
Registry record updatedJanuary 8, 2025
Trial IDNCT06763419 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals with painful clicking in the TMJ area and pain in the lateral pterygoid muscle who have a full set of natural teeth.

Probably not a fit

Patients with degenerative TMJ conditions, recent trauma, or systemic diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the effectiveness of internal and external photobiomodulation (PBM) therapies in managing patients with temporomandibular joint internal derangements (TMJ-ID). Participants will receive either internal or external low-level laser therapy to assess pain relief and functional improvement. The study focuses on individuals experiencing painful clicking in the TMJ area and pain in the lateral pterygoid muscle, while excluding those with certain dental or systemic conditions. The goal is to determine which method provides better outcomes for patients suffering from TMJ disorders.

Why it matters

Potential benefit: If successful, this study could offer a non-invasive treatment option for patients suffering from TMJ disorders.

How similar studies have gone: While there is ongoing research in photobiomodulation, this specific comparison of internal versus external methods is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Painful click at temporomandibular joint (TMJ) area.
* Pain at the lateral pterygoid muscle.
* Presence of full or nearly full complement of natural teeth with acceptable occlusion

Exclusion Criteria:

* Patients who have radiographic evidence of degenerative conditions of TMJ.
* Patients under current dental or physical therapy that could affect TMD.
* History of recent trauma.
* The presence of systemic diseases (i.e. rheumatoid arthritis, osteoarthritis).
* Pregnant and lactating females.
* Presence of open bite.

Where it's running

  • Faculty of Dentistry
    Alexandria, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.