Condition

Sedation clinical trials and research

• 15Clinical trials
• 8NIH research projects
• 7Countries

Newest Sedation clinical trials

All recruiting trials (15)

• Perioperative risks in adults with Brugada syndrome during anesthesia and related procedures

  This registry follows adults with Brugada syndrome to see how often dangerous heart rhythms occur around anesthesia and up to 30 days after.

  Recruiting Hospital Clinic of Barcelona · Barcelona, Barcelona · NCT07655102

• Neonatal Neurological Observation With Video AI

  This study tests a real-time, non-contact video AI system to help monitor brain health in newborns with suspected brain injury during their hospital stay.

  Recruiting Artemis AI Labs · New York, New York and 1 other locations · NCT07628829

• Remimazolam sedation in ICU patients on mechanical ventilation

  This study tests whether using remimazolam for sedation helps mechanically ventilated ICU patients recover better compared to another sedative.

  Recruiting Phase 3 Southeast University, China · Nanjing, Jiangsu · NCT07596589

• Sedation with dexmedetomidine, propofol, or both during cataract surgery

  This project will test whether dexmedetomidine, propofol, or their combination (each given with fentanyl) provides the best sedation, safety, and surgeon satisfaction for adults having cataract surgery.

  Recruiting Saint-Joseph University · Beirut · NCT07556133

• Light exposure during general anesthesia

  This test checks whether covering patients' eyes during general anesthesia changes how much anesthetic adults (18–65) need.

  Recruiting Peking University People's Hospital · Beijing · NCT07517484

• Comparing two propofol dosing models for sedated ICU patients on ventilators

  This study will test whether the Eleveld or Schnider dosing model gives steadier propofol sedation for adults on mechanical ventilation in the ICU.

  Recruiting Hacettepe University · Ankara · NCT07239687

• Bispectral monitoring to guide sedation in mechanically ventilated ICU patients

  This study tests whether using BIS monitoring while patients are sedated on ventilators changes how long they stay on ventilation, ICU stay, and the total amount of sedation given.

  Recruiting The University of Texas Health Science Center, Houston · Cypress, Texas · NCT07219069

• Million Anesthesia Cases: Preoperative fasting and perioperative outcomes

  This project will see if longer pre-surgery fasting harms people having procedures with anesthesia by looking at symptoms like hunger and thirst, physiologic changes such as low blood pressure and blood sugar shifts, and risks like aspiration and nausea.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07022951

• Virtual reality with hypnosis to lower anxiety and sedation during regional anesthesia for limb surgery

  The team will try virtual reality combined with hypnosis to reduce anxiety and the need for sedatives in adults having scheduled upper or lower limb orthopedic surgery under regional anesthesia.

  Recruiting Centre Hospitalier Eure-Seine · Évreux · NCT07013695

• Inhaled isoflurane versus IV propofol for sedation of ventilated ICU patients

  This trial will test whether inhaled isoflurane delivered through the Sedaconda ACD‑S shortens time on the ventilator compared with intravenous propofol in adults needing deep sedation and expected to require mechanical ventilation for more than 48 hours.

  Recruiting at 12 sites Phase 4 Instituto de Investigación Hospital Universitario La Paz · Orihuela, Alicante and 21 other locations · NCT07000526

• Comparing High Flow Nasal Oxygen and Nasal Cannula for Burn Patients Under Sedation

  This study is testing whether high flow nasal oxygen can help burn patients breathe better during surgery compared to standard nasal oxygen.

  Recruiting Ankara City Hospital Bilkent · Ankara · NCT06756906

• Monitoring brain activity in ICU patients with sedation and delirium

  This study is testing a new brain monitoring device to see if it can help doctors better understand sedation and delirium in patients who are intubated and sedated in the ICU.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06718764

• Using Remimazolam for Sedation in Patients After Heart Surgery

  This study tests if a new sedative called remimazolam can help heart surgery patients recover better and get off breathing machines faster compared to a standard sedative.

  Recruiting First Affiliated Hospital of Zhejiang University · Hangzhou, Zhejiang · NCT06716840

• Assessing the safety and effectiveness of remazolam besylate for sedation in critically ill patients on ventilators after surgery

  This study is testing if a new sedative called remazolam besylate is safe and effective for helping critically ill patients on ventilators after surgery, compared to a standard sedative.

  Recruiting Phase 4 Beijing Shijitan Hospital, Capital Medical University · Beijing, Beijing Municipality · NCT06575530

• Nebulized dexmedetomidine with ketamine versus dexmedetomidine alone for sedation in children having cleft palate repair

  This will test whether adding ketamine to nebulized dexmedetomidine helps sedate children undergoing cleft palate repair and reduces emergence delirium.

  Recruiting Phase 4 Assiut University · Asyut · NCT05821972

NIH-funded research (8)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Pediatric ICU Sedation and Brain Recovery after Injury

  This grant studies how sedation given in the pediatric ICU affects short- and long-term brain recovery in children who have suffered brain injuries.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11528580

• Reducing deep sedation in ICU to improve recovery after respiratory failure

  Aims to help adults on ventilators avoid deep sedation to improve survival and quality of life after critical illness.

  NIH research New York University · New York, United States · NIH-11364618

• Sedation and brain recovery after cardiac arrest

  This project looks at whether different sedation approaches help adults recover brain function after a cardiac arrest.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11284021

• Investigating how sedation affects recovery after cardiac arrest

  This study is looking at how sedation affects brain recovery in people who have had a cardiac arrest, to see if being sedated helps their brain function better after they start to wake up.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11035211

• Effects of long sedation on infant brain development

  This study is looking at how long periods of sedation during critical care might affect the brain development of infants, especially those with a specific condition called congenital long-gap esophageal atresia, to help us understand how these effects relate to their growth and development by the time they turn one yea

  NIH research Boston Children's Hospital · Boston, United States · NIH-10929935

• Improving sedation methods to reduce brain dysfunction in ventilated children

  This study is looking at how different ways of calming young kids on breathing machines in the hospital can affect their brain health, comparing a common medicine with a newer one to see which is better for their recovery.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10912645

• Understanding blood flow and oxygen levels in children's brains during anesthesia

  This study looks at how anesthesia impacts blood flow and oxygen in the brains of babies and young kids, helping doctors understand any risks so they can provide safer care for children who need surgery or other procedures.

  NIH research Children's Hospital of Los Angeles · Los Angeles, United States · NIH-10907518

• Improving sedation and pain management for critically ill children

  This study is looking at how to give the right amount of medicine to help kids feel less pain and anxiety during tough medical procedures, so they can recover better and stay safe while getting the care they need.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-10802191

Related topics

Quick answers

How many Sedation clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (4 trials), China (4 trials), Turkey (Türkiye) (2 trials), Spain (2 trials), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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