Perioperative risks in adults with Brugada syndrome during anesthesia and related procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational registry collects data on adults with Brugada syndrome undergoing any anesthetic or sedation procedure. It aims to quantify the incidence of malignant ventricular arrhythmias during anesthesia and within 30 days post-procedure, and to examine whether certain anesthetic drugs thought to be risky are linked to higher arrhythmic events. The study also analyzes how perioperative factors like blood pressure changes, fever, and bradycardia may contribute to arrhythmia risk. Data will be collected from clinical records at participating centers to characterize perioperative management and outcomes.

Why it matters

Who can join: the full rules

Patients should match all the inclusion criteria to be entered for data collection:

* Documented type 1 Brugada ECG pattern (spontaneous, fever-related, or induced by sodium-channel blocker challenge/other recognised provocation test) with a diagnosis considered compatible with Brugada syndrome by the treating cardiology team.
* Undergoing general anaesthesia, monitored sedation, loco-regional anaesthesia for any surgical, diagnostic, interventional, obstetric or other non-surgical procedure (including epidural analgesia for labour and sedation for endoscopy).

Patients with one or more exclusion criteria will not be included for data collection and analysis:

* No documented type 1 Brugada ECG pattern, uncertain diagnosis without sufficient supporting data.
* Refusal to participate in the study.

Where it's running

• Hospital Clinic de Barcelona
  Barcelona, Barcelona, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.