Understanding blood flow and oxygen levels in children's brains during anesthesia
Investigation of Cerebral Hemodynamics and Oxygenation Relationships Under Sedation in Children: ICHOR USC
['FUNDING_OTHER'] · CHILDREN'S HOSPITAL OF LOS ANGELES · NIH-10907518
This study looks at how anesthesia impacts blood flow and oxygen in the brains of babies and young kids, helping doctors understand any risks so they can provide safer care for children who need surgery or other procedures.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CHILDREN'S HOSPITAL OF LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10907518 on ClinicalTrials.gov |
What this research studies
This research investigates how anesthesia affects blood flow and oxygen levels in the brains of infants and young children. Using advanced neuroimaging techniques, the study aims to measure the changes in cerebral blood flow and metabolism during sedation. By comparing these responses in infants with different health conditions, the researchers hope to identify potential risks associated with anesthesia. The findings could lead to better monitoring and treatment strategies for vulnerable pediatric patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants and young children undergoing anesthesia for medical procedures.
Not a fit: Patients who are not undergoing anesthesia or are older than 21 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could improve the safety and outcomes of anesthesia in infants and young children.
How similar studies have performed: Previous research has shown promising results in understanding cerebral hemodynamics in adults, but this specific focus on pediatric patients is relatively novel.
Where this research is happening
LOS ANGELES, UNITED STATES
- CHILDREN'S HOSPITAL OF LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BORZAGE, MATTHEW — CHILDREN'S HOSPITAL OF LOS ANGELES
- Study coordinator: BORZAGE, MATTHEW
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury