Investigating how sedation affects recovery after cardiac arrest
Role of Sedation in the Post-Cardiac Arrest Neurological Recovery
This study is looking at how sedation affects brain recovery in people who have had a cardiac arrest, to see if being sedated helps their brain function better after they start to wake up.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11035211 on NIH RePORTER |
What this research studies
This research explores the impact of sedation on neurological recovery in patients who have experienced cardiac arrest. It aims to understand how sedation may influence brain function and recovery after patients regain spontaneous circulation. The study will utilize quantitative electroencephalogram (EEG) to monitor brain activity and assess the effects of different sedation levels on cerebral blood flow and metabolism. By comparing outcomes in sedated versus non-sedated patients, the research seeks to clarify the role of sedation in improving recovery.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced a cardiac arrest and are undergoing treatment in an intensive care unit.
Not a fit: Patients who have not experienced cardiac arrest or those who are not in a comatose state post-cardiac arrest may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery strategies for patients who survive cardiac arrest, potentially enhancing their neurological outcomes.
How similar studies have performed: While some studies have explored sedation effects in other contexts, this specific investigation into sedation's role in post-cardiac arrest recovery is relatively novel and untested.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Ichinose, Fumito — Massachusetts General Hospital
- Study coordinator: Ichinose, Fumito
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.