Condition

Psychiatric Disorders clinical trials and research

• 10Clinical trials
• 36NIH research projects
• 7Countries

Newest Psychiatric Disorders clinical trials

All recruiting trials (10)

• French validation of the Recovery Assessment Scale for mental health

  This study tests whether a French version of the Recovery Assessment Scale works well for adults receiving psychiatric care.

  Recruiting Etablissement Public de Santé Mentale de Metz-Jury · Jury, Moselle · NCT07667686

• Lemborexant for insomnia in people with psychiatric conditions

  We will try lemborexant for 8 weeks in adults with psychiatric disorders who have insomnia to see if it helps them sleep better and is safe.

  Recruiting at 9 sites Shanghai Mental Health Center · Suzhou, Jiangsu and 8 other locations · NCT07417813

• Virtual reality schema therapy exercises with parent and child modes

  This study tests whether virtual-reality dialogue exercises using parent and child avatars are feasible and helpful for adults (18–65) with psychiatric symptoms linked to early-life experiences.

  Recruiting University Medical Center Groningen · Groningen, Provincie Groningen · NCT07373223

• Psychiatric disorders' influence on relapse during complex detox

  This project will test whether screening for psychiatric diagnoses can help predict and reduce relapse risk in people aged 16 and older hospitalized for complex detox at CHU de Strasbourg.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07023419

• Effectiveness of the SKILLS Program for Mental Health Care

  This study tests whether the SKILLS psychotherapy program can help adults with a psychiatric disorder improve their mental health.

  Recruiting University Hospital, Tours · Tours · NCT06622993

• Gaze-Contingent Music Therapy to Help Kids with Anxiety

  This study is testing if adding a special music therapy to regular talk therapy can help kids and teens with anxiety feel better.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06595953

• Treatment for individuals involved with the criminal justice system to assess and prevent suicide risk

  This study is testing a new way to help people in the criminal justice system who are at risk of suicide by using health and jail records to provide better support and treatment.

  Recruiting Cambridge Health Alliance · Cambridge, Massachusetts · NCT06564948

• Testing melatonin and low-dose quetiapine for insomnia in patients with psychiatric disorders

  This study is testing whether melatonin and a low dose of quetiapine can help people with psychiatric disorders sleep better compared to a placebo.

  Recruiting Phase 2/3 University of Copenhagen · Copenhagen NV · NCT06062953

• Exploring personality disorders in older adults

  This study is trying to see if new questionnaires can help better understand and treat personality disorders in older adults.

  Recruiting Universitair Ziekenhuis Brussel · Tienen, Vlaams-Brabant and 1 other locations · NCT05548946

• Group-based treatment for insomnia in psychiatric patients

  This study is testing a group therapy program for insomnia to see if it helps people with sleep problems and mental health issues feel better.

  Recruiting Haukeland University Hospital · Bergen · NCT04463498

NIH-funded research (36)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Whole-chromosome fine-mapping across diverse ancestries to understand psychiatric disorders

  A study to pinpoint the exact genetic changes that contribute to bipolar disorder and related conditions by using diverse populations to improve accuracy.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11515882

• Neuronal signals guiding deep brain stimulation for neuropsychiatric disorders

  A doctor-scientist at Stanford plans to study how deep brain stimulation changes brain cells and circuits in people with OCD, depression, and movement disorders to improve how DBS therapies work.

  NIH research Stanford University · Stanford, United States · NIH-11438671

• How a spouse's mental health and substance use may affect a partner's drinking problems

  A study looks at how a spouse’s psychiatric disorders and drinking habits influence when a person starts, stops, or relapses into alcohol use problems within marriage.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11383424

• Mapping brain microstructure in psychiatric disorders with normal ranges

  A study will build a brain-mapping reference to understand how an individual’s brain differs within the normal range, with a focus on youths and how age and sex affect brain microstructure.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11372272

• Foundation Models for Brain Imaging in Psychiatry

  A large AI model will be trained on many brain scans and related data to help researchers understand ADHD, autism, and bipolar disorder.

  NIH research Stanford University · Stanford, United States · NIH-11372161

• How early pollution and stress change brain circuits for motivation and memory

  This work looks at how early-life exposure to pollution and stress can alter brain circuits that control motivation and working memory for people with ADHD, depression, or similar conditions.

  NIH research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · New York, United States · NIH-11295458

• Basal forebrain and brain networks in psychiatric disorders

  This grant aims to understand how a brain region called the basal forebrain helps regulate thinking and attention in people with severe mental illness, with the goal of guiding new treatments.

  NIH research VA Boston Health Care System · Boston, United States · NIH-11290806

• Brain-targeted estradiol therapy for stress-related mental health in Veterans

  Researchers are developing a brain-targeted form of estradiol to help Veterans with depression, anxiety, and PTSD.

  NIH research Baltimore VA Medical Center · Baltimore, United States · NIH-11264819

• Shared brain and genetic patterns across psychiatric conditions

  This project looks for common brain and gene patterns in people with autism, ADHD, and related psychiatric conditions to help guide diagnosis and treatment.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11261776

• Thalamus-to-cortex wiring problems in psychiatric and developmental conditions

  This project uses human stem-cell models to look at how early wiring between the thalamus and cortex can go wrong in people with 22q11.2 deletion, autism, or ADHD.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11256718

• How mercury and selenium together may affect teen brain development and later mental health

  This work looks at whether low-level mercury exposure during adolescence combined with different selenium diets can harm brain cells linked to mood and behavior in teens and young adults.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11251924

• Blood-vessel signals that shape brain development in autism and other psychiatric conditions

  Researchers are looking at how signals from blood vessels in the developing brain may contribute to autism and other psychiatric conditions.

  NIH research Huntington Medical Research Institutes · Pasadena, UNITED STATES · NIH-11247972

• Helping Veterans with Mental Health Issues Find and Keep Jobs

  This study is all about helping veterans with mental health challenges find and keep jobs by making career counseling better and more supportive, so they can feel more confident about their work goals and get the help they need.

  NIH research Edith Nourse Rogers Memorial Veterans Hospital · Bedford, United States · NIH-11191389

• Mapping Brain Differences in Mental Health Conditions

  This project looks at individual brain differences to better understand mental health conditions and how treatments might work best for each person.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11142563

• How a spouse's mental health affects alcohol problems during marriage

  This project looks at whether a spouse's psychiatric problems or genetic risk change when married people develop, recover from, or relapse into alcohol use disorder.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11122205

• Investigating how a specific chloride transporter affects brain function in models of psychiatric disorders

  This study is looking at how a specific brain system affects thinking and social behavior in models of schizophrenia, and it tests whether a medication called bumetanide can help improve brain function and cognitive skills in people with this condition.

  NIH research Northwestern University at Chicago · Chicago, United States · NIH-11114186

• Using estradiol to treat stress-related mental health issues in Veterans

  This study is looking at how a hormone called estradiol might help improve mental health for Veterans dealing with stress-related issues like depression and PTSD, by exploring how it works in the brain and aiming to create a safer treatment option.

  NIH research Baltimore VA Medical Center · Baltimore, United States · NIH-11098416

• Understanding Brain and Immune System Links in Psychiatric Conditions

  This research explores how the immune system might affect brain development and lead to psychiatric conditions like schizophrenia in young people.

  NIH research University of California at Davis · Davis, United States · NIH-11063282

• Understanding how the basal forebrain affects brain networks in psychiatric disorders

  This study is looking at how a part of the brain called the basal forebrain affects thinking and memory in people with schizophrenia, especially since their brain's default mode network often doesn't work well; the researchers hope to find new ways to help improve these cognitive issues.

  NIH research VA Boston Health Care System · Boston, United States · NIH-11061842

• How environmental toxins affect brain circuits related to psychiatric disorders.

  This study looks at how things like pollution and stress during childhood can affect the brain's ability to handle rewards and memory, especially in people facing tough economic situations, to help us understand mental health issues like depression, schizophrenia, and ADHD.

  NIH research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · New York, United States · NIH-11060950

• Investigating the long-term effects of early arsenic exposure on mental health

  This study is looking at how being exposed to small amounts of arsenic in things like well water and food when we're young might lead to mental health issues like depression and anxiety later on, using zebrafish to help us understand how this happens in our brains.

  NIH research Mount Desert Island Biological Lab · Salsbury Cove, United States · NIH-11059163

• Exploring the shared genetic and neural factors in psychiatric disorders

  This study is looking at how our genes and brain activity are connected to mental health issues, with the goal of finding new ways to help people manage and treat these conditions better.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11047260

• How mercury and selenium affect brain development and mental health

  This study looks at how being exposed to small amounts of mercury and having different levels of selenium might affect brain development in teenagers and could increase the risk of mental health problems later on.

  NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11032032

• Understanding genetic changes linked to psychiatric disorders

  This study is looking at specific genetic changes linked to conditions like autism and schizophrenia to better understand how they affect people, with the hope of finding new ways to diagnose and treat these disorders.

  NIH research Stanford University · Stanford, United States · NIH-11013840

• Investigating how genetic mutations affect brain development related to psychiatric disorders

  This study is looking at how certain genes affect the way brain connections develop, especially those that help us process senses and think, to better understand conditions like autism and ADHD, which could lead to new treatment options for those affected.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11010809

• Mapping genetic variations linked to psychiatric disorders across different ancestries

  This study is working to better understand how our genes can affect mental health by looking closely at genetic information from different backgrounds, especially those that are often overlooked, so that researchers can find the specific genes linked to psychiatric disorders and help everyone more effectively.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-10984631

• Understanding brain structure differences in psychiatric disorders

  This study is looking at the tiny structures in the brains of people with mental health conditions to create a helpful guide that shows how these structures can vary, which could lead to more personalized treatments for everyone.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10918155

• Investigating the genetic links between substance use and psychiatric disorders

  This study is looking at how tobacco addiction and mental health issues like schizophrenia might be linked through shared genetics, with the hope of finding new ways to improve treatment for people dealing with both challenges.

  NIH research Centre for Addiction and Mental Health · Toronto, Canada · NIH-10918045

• Understanding mental health risks after kidney transplants

  This study is looking at what might cause mental health issues like depression and PTSD in people who have had a kidney transplant, so we can better support them and understand who might need extra help.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10896476

• How a spouse's mental health affects their partner's alcohol use problems

  This study looks at how one partner's mental health issues or substance use can affect the drinking habits of their spouse, helping us understand how these challenges can influence each other in couples dealing with alcohol use disorder.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10893483

• Investigating a new treatment for neurological and psychiatric disorders through mGlu7 receptor modulation

  This study is looking at a special brain receptor that could help improve thinking and behavior in people with conditions like autism and Rett syndrome by testing a new compound that might reduce anxiety, boost cognitive skills, and lessen seizures.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-10884237

• The effects of air pollution on male-biased psychiatric disorders in youth

  This study is looking at how breathing in polluted air while growing up might lead to mental health issues, especially in boys, like schizophrenia and autism, by using animal models to see how it affects their brains and behavior.

  NIH research University of Rochester · Rochester, United States · NIH-10880513

• Investigating how air pollution affects emotional development and mental health risks.

  This study is looking at how air pollution, like tiny particles and nitrogen dioxide, affects the emotions and behaviors of kids and teens, especially focusing on how being exposed to this pollution before and during childhood might impact their brain development and mental health.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-10873864

• Targeting brain circuits to treat epilepsy and mental health disorders

  This study is exploring new ways to control certain brain cells to better understand and treat conditions like epilepsy and mental health issues, using special tools that could eventually help people.

  NIH research Broad Institute, INC. · Cambridge, United States · NIH-10783786

• Investigating how prenatal factors affect brain development and mental health in children

  This study looks at how certain substances in pregnant mothers' blood might affect the chances of their children developing schizophrenia or autism, hoping to find ways to support healthier brain development and mental health in kids.

  NIH research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · New York, United States · NIH-10756456

• Exploring genetic factors in psychiatric disorders using big data

  This study is looking at how certain genes that don’t make proteins might affect mental health conditions, using advanced technology to better understand the brain, and it’s aimed at finding new ways to help people with psychiatric disorders.

  NIH research University of California-Irvine · Irvine, United States · NIH-10640918

Related topics

Quick answers

How many Psychiatric Disorders clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in France (3 trials), United States (2 trials), Netherlands (2 trials), China (1 trial), Norway (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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