Exploring personality disorders in older adults
Official title: Empirical Evaluation and Clinical Relevance of a Dimensional Model for Personality Disorders in Later Life
Run by Universitair Ziekenhuis Brussel · NCT05548946 · Data updated 2026-11-12
This study is trying to see if new questionnaires can help better understand and treat personality disorders in older adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 750 (estimated) |
| Sponsor | Universitair Ziekenhuis Brussel Academic / other |
| Locations | 2 sites (Tienen, Vlaams-Brabant and 1 other locations) |
| Status | Recruiting |
| Started | September 1, 2022 |
| Main results expected | November 2025 |
| Study ends | November 2025 |
| Registry record updated | December 9, 2024 |
| Trial ID | NCT05548946 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are Dutch-speaking older adults aged 65 and above who are experiencing personality disorders.
✕Probably not a fit
Patients with severe cognitive impairments or acute mental states that affect response reliability will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research focuses on understanding personality disorders (PDs) in older adults, a demographic often overlooked despite the prevalence of these disorders. The study aims to validate the Alternative Model for Personality Disorders (AMPD) and the ICD-11 approach specifically for older populations by utilizing self-report questionnaires designed to assess personality functioning. By examining the construct validity and age-neutrality of these instruments, the study seeks to improve the diagnosis and treatment of PDs in older adults. The findings could lead to better tailored mental health care for this age group.
Why it matters
Potential benefit: If successful, this study could enhance the diagnosis and treatment of personality disorders in older adults, leading to improved mental health outcomes.
How similar studies have gone: While early research indicates promise for dimensional classification in older adults, this approach is still relatively novel and requires further validation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Clinical population (inpatients and outpatients) Inclusion Criteria: * ONLY older adults: from the age of 65 * Dutch speaking Exclusion Criteria (as evaluated by the psychiatrists and psychologists of the participating institutions): * Severe cognitive impairment (Patients who are admitted because of cognitive impairment will be excluded from the participant pool, other than this the psychiatrists and psychologists of the participating institutions will make an evaluation of the patients' cognitive capacities) * Acute state of mental impairment which would interfere with the reliability of the patients' responses (for example severe psychosis), as evaluated by the psychiatrists and psychologist of the participating institutions.
Where it's running
-
Alexianen Zorggroep Tienen
Tienen, Vlaams-Brabant, Belgium Recruiting -
Mondriaan
Heerlen, Limburg, Netherlands Not yet recruiting
Study contacts
- Principal investigator: Morag Facon — Vrije Universiteit Brussel
- Study coordinator: Morag Facon
- Email: morag.flora.facon@vub.be
- Phone: +32493596294
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.