Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Exploring personality disorders in older adults

Official title: Empirical Evaluation and Clinical Relevance of a Dimensional Model for Personality Disorders in Later Life

Run by Universitair Ziekenhuis Brussel · NCT05548946 · Data updated 2026-11-12

This study is trying to see if new questionnaires can help better understand and treat personality disorders in older adults.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment750 (estimated)
SponsorUniversitair Ziekenhuis Brussel
Academic / other
Locations2 sites (Tienen, Vlaams-Brabant and 1 other locations)
StatusRecruiting
StartedSeptember 1, 2022
Main results expectedNovember 2025
Study endsNovember 2025
Registry record updatedDecember 9, 2024
Trial IDNCT05548946 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are Dutch-speaking older adults aged 65 and above who are experiencing personality disorders.

Probably not a fit

Patients with severe cognitive impairments or acute mental states that affect response reliability will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research focuses on understanding personality disorders (PDs) in older adults, a demographic often overlooked despite the prevalence of these disorders. The study aims to validate the Alternative Model for Personality Disorders (AMPD) and the ICD-11 approach specifically for older populations by utilizing self-report questionnaires designed to assess personality functioning. By examining the construct validity and age-neutrality of these instruments, the study seeks to improve the diagnosis and treatment of PDs in older adults. The findings could lead to better tailored mental health care for this age group.

Why it matters

Potential benefit: If successful, this study could enhance the diagnosis and treatment of personality disorders in older adults, leading to improved mental health outcomes.

How similar studies have gone: While early research indicates promise for dimensional classification in older adults, this approach is still relatively novel and requires further validation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Clinical population (inpatients and outpatients)

Inclusion Criteria:

* ONLY older adults: from the age of 65
* Dutch speaking

Exclusion Criteria (as evaluated by the psychiatrists and psychologists of the participating institutions):

* Severe cognitive impairment (Patients who are admitted because of cognitive impairment will be excluded from the participant pool, other than this the psychiatrists and psychologists of the participating institutions will make an evaluation of the patients' cognitive capacities)
* Acute state of mental impairment which would interfere with the reliability of the patients' responses (for example severe psychosis), as evaluated by the psychiatrists and psychologist of the participating institutions.

Where it's running

  • Alexianen Zorggroep Tienen
    Tienen, Vlaams-Brabant, Belgium
    Recruiting
  • Mondriaan
    Heerlen, Limburg, Netherlands
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.