Exploring the shared genetic and neural factors in psychiatric disorders
Official title: Shared neural basis and genetic architecture of psychiatric disorders
Funded at University of Pennsylvania · NIH-11047260 · Data updated 2026-11-12
This study is looking at how our genes and brain activity are connected to mental health issues, with the goal of finding new ways to help people manage and treat these conditions better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | January 21, 2025 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $702,928 |
| NIH project number | 1R01MH136055-01A1 |
| Project ID | NIH-11047260 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with psychiatric disorders such as ADHD, autism spectrum disorders, and bipolar affective disorder.
✕Less likely to help
Patients with psychiatric disorders that are not included in the study's focus may not receive any benefit from this research.
What this research studies
This research investigates the genetic and neural underpinnings of various psychiatric disorders by analyzing large-scale imaging and genetic data. It aims to identify objective biomarkers that can help in the risk management and treatment of these conditions. By integrating multi-organ imaging data and functional genomic resources, the study seeks to uncover complex biological mechanisms that may contribute to psychiatric disorders. Patients may benefit from improved understanding and potential new treatment strategies based on these findings.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and targeted treatments for psychiatric disorders.
How similar studies have gone: Previous research has shown promise in using multi-modal imaging and genetic data to understand psychiatric disorders, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Zhao, Bingxin — University of Pennsylvania
- Study coordinator: Zhao, Bingxin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.