See if the Morrow eProgressive lenses work better than standard PALs for presbyopia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 45 and older with presbyopia will try both the Morrow eProgressive and standard PALs for three weeks each, in random order, across three sites in Belgium and Italy. The trial uses a randomized, open-label, crossover design so each participant serves as their own control. Researchers will measure eye and head movements during reading, assess stair descent performance, and collect visual comfort and lens preference data through questionnaires. The primary endpoint focuses on objective dynamic visual performance via eye-tracking metrics, with additional secondary outcomes including user-reported comfort and overall satisfaction.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 45 or older, who are presbyopic in both eyes, with an inclusion criterium of minimum + 1.75 ADDition.
* Suitable candidate for Morrow glasses
* Willing and able to adhere to the study protocol and study procedures, and provide written consent prior to enrollment
* Willing and able to strictly adhere to the 2 x 3-week spectacle-wearing schedule for all standard day-to-day activities, including a commitment to exclusive progressive wear of the assigned study spectacles (traditional PAL or Morrow eProgressive) throughout each respective study phase (temporary exceptions for sports or specific occasions are permitted using single-vision solutions only).
* Current vision solution satisfaction below 8/10, as assessed by the study specific satisfaction questionnaire.

Exclusion Criteria:

* Individuals who do not yet require a reading addition for near tasks.
* Distant BCVA worse than 20/25 (Snellen) or \>0.1 LogMar
* Previous laser treatment for refractive correction.
* Any previous refraction and/or intra-ocular surgery.
* Any known systemic diseases affecting vision (e.g. diabetes, uncontrolled or unmedicated hypertension, autoimmune disease, inflammatory disease … ), at the discretion of the investigator
* Associated strabismus (eyes not properly aligned)
* Associated amblyopia (lazy eye)
* Currently undergoing orthoptics therapy (exercises or treatments to fix eye movement problems or double vision)
* Associated anisometropia \> 1.5 diopters

Where it's running

• University Hospital Antwerp
  Antwerp, Belgium Recruiting
• Meclinas
  Mechelen, Belgium Not yet recruiting
• Research Centre in Optics & Optometry (COMiB), University of Milano Bicocca
  Milan, Italy Not yet recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Volumetric visual fields with occupational vs general-purpose progressive lenses in presbyopia

  This study tests whether two occupational progressive lenses and a general-purpose PAL give different depth of clear vision at multiple distances for people with presbyopia.

  Recruiting University of Seville · Seville, Andalusia · NCT07870785

• Trying DAILIES TOTAL1 Multifocal Lenses in satisfied INFUSE wearers

  This study tests whether switching satisfied INFUSE One-Day Multifocal wearers to DAILIES TOTAL1 Multifocal lenses maintains comfort and clear vision.

  Recruiting Gordon Schanzlin New Vision · La Jolla, California · NCT07638943

• VisAbility Micro Insert System for Presbyopia

  A new device called the VisAbility Micro Insert System is being tested to see if it can improve near vision at reading distance for adults with presbyopia.

  Recruiting at 2 sites VisDura, Inc. · Bochum and 1 other locations · NCT07637500

• Volumetric visual fields with progressive lenses for presbyopia at intermediate and near distances

  Researchers will test two occupational progressive lenses to see which provides a larger clear field at intermediate and near distances for people with presbyopia.

  Recruiting University of Seville · Seville, Andalusia and 1 other locations · NCT07617090

• Total30 Multifocal Toric Contact Lenses in Presbyopic Toric Wearers

  This study tests whether Total30 MFT toric contact lenses are comfortable and acceptable for people who already wear reusable toric lenses and are now presbyopic.

  Recruiting Southern College of Optometry · Memphis, Tennessee · NCT07586982

• A Smart Aperture Lens to Help Keratoconus and Presbyopia

  This study tests the NOA lens, a custom scleral contact lens with a central aperture, to see if it improves vision for people with keratoconus and presbyopia.

  Recruiting at 2 sites Azalea Vision · Antwerp and 1 other locations · NCT07559188

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.