Clinical trial Recruiting at 1 site Interventional Ages 52 to 67

Volumetric visual fields with occupational vs general-purpose progressive lenses in presbyopia

Official title: Ensayo clínico, unicéntrico, Transversal, Randomizado, Cruzado, Doble Ciego Para Evaluar Las Diferencias de Los Campos volumétricos de visión en Pacientes présbitas, Entre 400 y 40 cm., de Tres Tipos de Lentes oftálmicas Neutras de Lejos y adición Progresiva de 2 D. Dos de visión Intermedia y Cerca OPL (PC-133 y PC-200), y Otra Generalista PAL de visión Lejos, Intermedia y Cerca (FIT-FRM).

Run by University of Seville · NCT07870785 · Data updated 2026-11-12

This study tests whether two occupational progressive lenses and a general-purpose PAL give different depth of clear vision at multiple distances for people with presbyopia.

Quick facts

Study typeInterventional
Ages52 Years to 67 Years
SexAll
Enrollment28 (estimated)
SponsorUniversity of Seville
Academic / other
Locations1 site (Seville, Andalusia)
StatusRecruiting
StartedJune 8, 2026
Main results expectedJune 26, 2026
Study endsJune 30, 2027
Registry record updatedOctober 15, 2026
Trial IDNCT07870785 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with presbyopia, spherical error within ±4.00 D and astigmatism ≤ 1.00 D, VA ≥ 0.8, and specific nasopupillary distance (NPD) makeup.

Probably not a fit

Individuals with higher astigmatism, prior cataract or certain intraocular lens histories, or different spectacle paradigms may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, randomized, double-blind, crossover trial that compares how much clear vision is available at different working distances when using two occupational progressive lenses (OPLs) designed for intermediate and near vision and a general-purpose progressive lens. Participants undergo standard optometric assessments and then have visual field measurements with each lens under controlled conditions. The study uses a fixed sequence and blinded evaluation to determine differences in volumetric visual fields across lenses. Outcomes focus on the extent of clear vision across distance ranges, not just acuity at a single distance.

Why it matters

Potential benefit: If successful, patients may gain lenses that provide broader clear vision across working distances for presbyopia.

How similar studies have gone: Previous research has explored visual fields with progressive lenses, but this specific cross-over comparison of occupational and general-purpose lenses for volumetric fields is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Spherical ametropia for distance vision ≤ ±4.00 D and astigmatic ametropia ≤ 1.00 D.

  * Decimal VA ≥ 0.8, either uncorrected (UCVA) or corrected (BCVA) with monofocal contact lenses.
  * Patients with a nasopupillary distance (NPD) of 31 mm, with a tolerance of ±2 mm in each eye

Exclusion Criteria:

* Astigmatism greater than ±1.00 D.
* Patients wearing progressive contact lenses.
* Patients who have undergone cataract surgery or have monofocal or multifocal intraocular lenses.
* Anisometropia greater than 2.50 D.
* Decimal distance visual acuity \< 0.8 (UCVA or BCVA) with monofocal contact lenses.

Where it's running

  • Pharmacy School, University of Seville
    Seville, Andalusia, Spain
    Recruiting

Study contacts

  • Principal investigator: José Manuel Serrano Morales, PhD — Pharmacy School, University of Seville
  • Study coordinator: José Manuel Serrano Morales, PhD
  • Email: jsmorales@us.es
  • Phone: 0034654686850

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.