Volumetric visual fields with occupational vs general-purpose progressive lenses in presbyopia
Official title: Ensayo clínico, unicéntrico, Transversal, Randomizado, Cruzado, Doble Ciego Para Evaluar Las Diferencias de Los Campos volumétricos de visión en Pacientes présbitas, Entre 400 y 40 cm., de Tres Tipos de Lentes oftálmicas Neutras de Lejos y adición Progresiva de 2 D. Dos de visión Intermedia y Cerca OPL (PC-133 y PC-200), y Otra Generalista PAL de visión Lejos, Intermedia y Cerca (FIT-FRM).
Run by University of Seville · NCT07870785 · Data updated 2026-11-12
This study tests whether two occupational progressive lenses and a general-purpose PAL give different depth of clear vision at multiple distances for people with presbyopia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 52 Years to 67 Years |
| Sex | All |
| Enrollment | 28 (estimated) |
| Sponsor | University of Seville Academic / other |
| Locations | 1 site (Seville, Andalusia) |
| Status | Recruiting |
| Started | June 8, 2026 |
| Main results expected | June 26, 2026 |
| Study ends | June 30, 2027 |
| Registry record updated | October 15, 2026 |
| Trial ID | NCT07870785 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with presbyopia, spherical error within ±4.00 D and astigmatism ≤ 1.00 D, VA ≥ 0.8, and specific nasopupillary distance (NPD) makeup.
✕Probably not a fit
Individuals with higher astigmatism, prior cataract or certain intraocular lens histories, or different spectacle paradigms may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, randomized, double-blind, crossover trial that compares how much clear vision is available at different working distances when using two occupational progressive lenses (OPLs) designed for intermediate and near vision and a general-purpose progressive lens. Participants undergo standard optometric assessments and then have visual field measurements with each lens under controlled conditions. The study uses a fixed sequence and blinded evaluation to determine differences in volumetric visual fields across lenses. Outcomes focus on the extent of clear vision across distance ranges, not just acuity at a single distance.
Why it matters
Potential benefit: If successful, patients may gain lenses that provide broader clear vision across working distances for presbyopia.
How similar studies have gone: Previous research has explored visual fields with progressive lenses, but this specific cross-over comparison of occupational and general-purpose lenses for volumetric fields is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Spherical ametropia for distance vision ≤ ±4.00 D and astigmatic ametropia ≤ 1.00 D. * Decimal VA ≥ 0.8, either uncorrected (UCVA) or corrected (BCVA) with monofocal contact lenses. * Patients with a nasopupillary distance (NPD) of 31 mm, with a tolerance of ±2 mm in each eye Exclusion Criteria: * Astigmatism greater than ±1.00 D. * Patients wearing progressive contact lenses. * Patients who have undergone cataract surgery or have monofocal or multifocal intraocular lenses. * Anisometropia greater than 2.50 D. * Decimal distance visual acuity \< 0.8 (UCVA or BCVA) with monofocal contact lenses.
Where it's running
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Pharmacy School, University of Seville
Seville, Andalusia, Spain Recruiting
Study contacts
- Principal investigator: José Manuel Serrano Morales, PhD — Pharmacy School, University of Seville
- Study coordinator: José Manuel Serrano Morales, PhD
- Email: jsmorales@us.es
- Phone: 0034654686850
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.