Investigating lens mechanics in aging eyes to improve vision

Combining OCE and Brillouin microscopy to evaluate in vivo lens biomechanics in Presbyopia

['FUNDING_FELLOWSHIP'] · UNIV OF MARYLAND, COLLEGE PARK · NIH-11036250

This study is looking at how the eye's lens changes as we get older, especially for people who have trouble seeing things up close, and it hopes to find new ways to help improve vision for those affected by this common issue.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIV OF MARYLAND, COLLEGE PARK (nih funded)
Locations1 site (COLLEGE PARK, UNITED STATES)
Trial IDNIH-11036250 on ClinicalTrials.gov

What this research studies

This research focuses on understanding how the lens of the eye changes with age, particularly in relation to presbyopia, a common condition that affects the ability to focus on close objects. By using advanced imaging techniques like optical coherence elastography (OCE) and Brillouin microscopy, the study aims to measure the mechanical properties of the lens in real-time. This approach could help identify the underlying causes of presbyopia and inform the development of new treatments that restore the eye's ability to accommodate. Patients may be involved in providing data that could lead to better therapeutic options for vision correction.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults experiencing presbyopia or age-related vision changes.

Not a fit: Patients with presbyopia who are not willing or able to participate in advanced imaging techniques may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to innovative treatments that restore dynamic vision in individuals suffering from presbyopia.

How similar studies have performed: While the techniques used in this research are promising, they are still in early clinical stages, and similar approaches have shown varying levels of success.

Where this research is happening

COLLEGE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.