LBV vs traditional monovision LASIK for presbyopia
Official title: Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study
Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT07512089 · Data updated 2026-11-12
In adults 40–55 with presbyopia, this study tests whether laser blended vision (LBV) provides better vision at distance, intermediate, and near after LASIK than traditional monovision LASIK.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 55 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Zhongshan Ophthalmic Center, Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | May 12, 2026 |
| Main results expected | June 30, 2028 |
| Study ends | June 30, 2028 |
| Registry record updated | July 7, 2026 |
| Trial ID | NCT07512089 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 40–55 with presbyopia who are suitable for LASIK, have stable refractive status for at least 1 year, good distance acuity, and are willing to comply with follow-up.
✕Probably not a fit
Individuals who do not benefit may experience persistent visual discomfort, lack of improved multi-distance vision, or intolerance to the LASIK technique.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, randomized, parallel-group trial comparing two LASIK approaches for presbyopia. About 100 participants will be randomly assigned to receive either laser blended vision LASIK or traditional monovision LASIK and followed for 6 months after surgery. All participants will undergo standard preoperative evaluations, the LASIK procedures will be performed by experienced surgeons, and vision tests plus questionnaires will assess visual quality and safety. The main goal is to determine if LBV offers superior uncorrected vision across distances with comparable safety to monovision LASIK.
Why it matters
Potential benefit: If LBV proves better, patients may achieve improved single-use vision across distances with potentially less dependence on reading glasses.
How similar studies have gone: High-quality randomized trials comparing LBV with traditional monovision are limited, making this study among the first direct comparisons in presbyopia.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 40 to 55 years with presbyopia * Suitable candidates for LASIK surgery based on clinical evaluation * Stable refractive status for at least 1 year * Best corrected distance visual acuity within normal range * Willing and able to provide written informed consent * Willing to comply with study visits and follow-up Exclusion Criteria: * Previous ocular surgery * Corneal disease or abnormal corneal condition that may affect safety * Significant ocular disease affecting visual function * Severe dry eye or other ocular surface disorders * Systemic disease that may affect study participation * Inability to tolerate monovision or anisometropia * Any condition that the investigator considers unsuitable for the study
Where it's running
-
Zhongshan Ophthalmic Center
Guangzhou, Guangdong, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.