How EDOF lens implants change eye light sensitivity after presbyopic correction
Impact of Artificial Lighting on Visual Acuity After Presbyopia Correction With an Extended Depth of Focus Intraocular Lens: Introduction of a Modified Luminous Efficiency Function V(λ)'
Democritus University of Thrace · NCT07077967
This will test whether people aged 45–75 who had EDOF intraocular lens implants need different lighting levels to reach their best vision.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 45 Years to 75 Years |
| Sex | All |
| Sponsor | Democritus University of Thrace (other) |
| Locations | 1 site (Alexandroupoli, Evros) |
| Trial ID | NCT07077967 on ClinicalTrials.gov |
What this trial studies
This observational study measures how extended‑depth-of-focus (EDOF) intraocular lenses modify total eye light transmittance and the luminous efficiency function in pseudophakic patients treated for presbyopia. Participants who meet the inclusion and exclusion criteria will have their visual acuity tested at varying controlled light intensities to identify the minimum light level required to reach maximal acuity compared with full lighting. Findings will be used to model a modified luminous efficiency function specific to this patient group and to estimate task and environmental lighting adjustments. The study is conducted at the University Hospital of Alexandroupolis and enrolls patients aged 45–75 without major ocular or systemic comorbidities.
Who should consider this trial
Good fit: Ideal candidates are adults 45–75 years old who have undergone pseudophakic presbyopic correction with EDOF IOLs, have postoperative uncorrected distance visual acuity of at least 8/10, and no major ocular or systemic exclusions listed in the protocol.
Not a fit: Patients with significant ocular disease (e.g., glaucoma, corneal or fundus disease), diabetes, autoimmune or neurological/psychiatric conditions, prior incisional eye surgery, astigmatism >1.00 D, posterior capsule rupture or lens misalignment are unlikely to benefit from the study findings.
Why it matters
Potential benefit: If successful, the results could provide practical lighting recommendations to help people with EDOF IOLs achieve better everyday vision and comfort.
How similar studies have performed: Previous research has examined IOL effects on vision and light transmission in limited contexts, but a specifically modified luminous efficiency function for EDOF IOL patients is novel and not well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age between 45 to 75 years Exclusion Criteria: * astigmatism \>1.00 diopters * glaucoma * former incisional eye surgery * corneal or fundus disease * diabetes mellitus * autoimmune diseases * neurological or psychiatric diseases * posterior capsule rupture or lens misalignment * postoperative uncorrected distance visual acuity \< 8/10.
Where this trial is running
Alexandroupoli, Evros
- University Hospital of Alexandroupolis — Alexandroupoli, Evros, Greece (RECRUITING)
Study contacts
- Study coordinator: Eirini - Kanella Panagiotopoulou, MD, MSc, PhD
- Email: panagiotopoulou.ek@gmail.com
- Phone: +30 6978730858
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Presbyopia, pseudophakic presbyopic correction, EDOF intraocular lens, light intensity, eye light transmittance, light efficiency function