Condition

Postoperative Pain, Acute clinical trials and research

• 17Clinical trials
• 8Countries

Newest Postoperative Pain, Acute clinical trials

All recruiting trials (17)

• Postoperative Pain Control in Elderly Knee Replacement

  This study tests two pain-management methods after knee replacement in adults 60 and older to see which one reduces delirium and improves recovery.

  Recruiting Ankara City Hospital Bilkent · Ankara, Çankaya · NCT07849517

• Anterior suprascapular nerve block vs interscalene block for shoulder surgery pain

  This trial tests whether an anterior suprascapular nerve block can provide similar pain relief to the standard interscalene block after outpatient shoulder surgery in adults.

  Recruiting ASST Sette Laghi · Varese, Italy · NCT07831096

• Compare TAP block vs ESP block for pain after laparoscopic kidney surgery

  Adults undergoing laparoscopic renal surgery will try either a TAP block or an ESP block to see which one better controls pain after surgery.

  Recruiting Cairo University · Cairo · NCT07781930

• Comfort Tote to help recovery after scoliosis surgery in teens

  This study tests whether a therapeutic Comfort Tote can reduce pain and anxiety after surgery for adolescent idiopathic scoliosis.

  Recruiting Columbia University · New York, New York · NCT07632833

• Ultrasound-guided SPS block versus surgeon intercostal block to prevent chronic pain after thoracoscopic (VATS) surgery

  This trial will test whether an ultrasound-guided Serratus Posterior Superior (SPS) block given before elective VATS reduces chronic post-thoracotomy pain compared with a surgeon-administered intercostal block.

  Recruiting Medipol University · Istanbul, Bagcilar · NCT07436806

• Ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block for shoulder arthroscopy pain

  This will test whether an ultrasound-guided serratus posterior superior intercostal plane (SPSIP) block reduces pain after arthroscopic shoulder surgery.

  Recruiting Bursa City Hospital · Bursa, Bursa · NCT07394673

• Timing nalbuphine for pain relief and blood pressure control during knee replacement in older adults

  We will test whether giving nalbuphine at different times during knee replacement helps control pain and stabilize blood pressure in people 65 and older.

  Recruiting Phase 4 Qianfoshan Hospital · Jinan, Shandong · NCT07271849

• External oblique intercostal (EOI) block to reduce pain after otoplasty with rib cartilage graft

  This trial will test whether an ultrasound-guided EOI nerve block with 0.2% ropivacaine reduces opioid use and pain in patients aged 13–18 having otoplasty with rib cartilage graft.

  Recruiting Seoul National University Hospital · Seoul · NCT07262944

• Meloxicam for pain after Mohs surgery

  This trial will try two doses of meloxicam plus acetaminophen versus acetaminophen with alternating ibuprofen to see which controls pain best for adults having Mohs skin cancer surgery.

  Recruiting Phase 4 University of Oklahoma · Oklahoma City, Oklahoma · NCT07200544

• Long-acting versus standard intercostal nerve block after thoracoscopic lung surgery

  This will test whether a long-acting liposomal bupivacaine intercostal nerve block reduces postoperative pain more than standard bupivacaine or usual care in adults having thoracoscopic lung cancer surgery.

  Recruiting Shanghai Pulmonary Hospital, Shanghai, China · Shanghai · NCT07134660

• Rectus Sheath Block technique comparison in adults

  This study tests two ultrasound-guided ways of delivering a rectus sheath block to see which method better spreads anesthetic and covers more nerves in adults having abdominal procedures.

  Recruiting Phase 2 Duke University · Durham, North Carolina · NCT07068243

• Optimal spinal morphine dose for pain after cesarean delivery

  This will test different doses of morphine given into the spinal fluid to find the best dose for reducing pain after an elective cesarean in adult women.

  Recruiting University of Ioannina · Ioannina, Epirus · NCT07023497

• PF614 for relieving pain after abdominoplasty surgery.

  This trial will test whether PF614, an extended-release oxycodone prodrug, reduces moderate-to-severe pain in adults after abdominoplasty surgery.

  Recruiting at 3 sites Phase 3 Ensysce Biosciences · Atlanta, Georgia and 2 other locations · NCT06602271

• Evaluating opioid-free pain management before urogynecologic surgeries

  This study is testing if a combination of pain relievers without opioids can help women recover faster after certain bladder surgeries.

  Recruiting Phase 4 Northwell Health · Bay Shore, New York · NCT06379425

• Effects of early mobilization on recovery after obesity surgery

  This study tests if getting up and moving around soon after obesity surgery helps patients recover faster and feel less pain.

  Recruiting Esbjerg Hospital - University Hospital of Southern Denmark · Esbjerg, Region Syddanmark · NCT06222151

• Pain control methods for patients undergoing esophagectomy

  This study is testing three different ways to manage pain for patients having minimally invasive esophagectomies to see which one works best.

  Recruiting Phase 1/2 Swedish Medical Center · Seattle, Washington · NCT05906134

• Using ketorolac for pain relief in lower limb surgeries

  This study tests if giving ketorolac at different times can help people having lower limb surgeries feel less pain after their operation.

  Recruiting Mansoura University · Al Mansurah · NCT05543785

Related topics

Quick answers

How many Postoperative Pain, Acute clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (6 trials), Turkey (Türkiye) (3 trials), China (2 trials), Egypt (2 trials), Greece (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 3: 1, Phase 2: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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