Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Compare TAP block vs ESP block for pain after laparoscopic kidney surgery

Official title: Comparison of Ultrasound-guided Transversus Abdominis Plane Block (TAP) and Erector Spinae Plane Block (ESPB) for Postoperative Analgesia in Adult Laparoscopic Renal Surgeries: A Randomized Controlled Trial.

Run by Cairo University · NCT07781930 · Data updated 2026-11-12

Adults undergoing laparoscopic renal surgery will try either a TAP block or an ESP block to see which one better controls pain after surgery.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment60 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedJanuary 5, 2026
Main results expectedAugust 2026
Study endsAugust 2026
Registry record updatedAugust 24, 2026
Trial IDNCT07781930 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18–40 years old with ASA I–II undergoing laparoscopic renal surgery who consent to participate.

Probably not a fit

Patients with coagulation disorders, allergies to local anesthetics, infection at the injection site, or significant renal/hepatic impairment may not benefit or be excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares ultrasound-guided TAP and ESP blocks for postoperative analgesia in adults undergoing laparoscopic renal procedures. Forty participants aged 18–60 with ASA I–II will be assigned to one of the two block techniques after induction of general anesthesia. Primary outcome is total fentanyl use within 24 hours, with pain scores and time to first analgesic request as secondary outcomes, along with safety measures. Blocks use 0.25% bupivacaine, performed under ultrasound guidance; outcome assessors are blinded to the block type. The study is conducted at Cairo University Hospitals with ethical approval and informed consent.

Why it matters

Potential benefit: If successful, the better-performing block could reduce opioid needs and improve postoperative comfort after renal laparoscopy.

How similar studies have gone: Previous work has explored TAP and ESP blocks in various surgeries, with mixed but promising signals for analgesic superiority depending on the setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Age from 18 to 40 years old.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I, II.
* Scheduled for laparoscopic renal surgeries under general anesthesia

Exclusion criteria:

* Parent's refusal.
* Coagulation disorders.
* History of allergy to local anesthetics.
* Infection or redness at the injection site.
* History of renal and/or hepatic insufficiency.
* Preexisting cardiac dysfunction.

Where it's running

  • Kasr Al-Ainy hospital
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.