Pain control methods for patients undergoing esophagectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized controlled trial aims to compare three different pain control methods in patients undergoing minimally invasive esophagectomies. Participants will be randomly assigned to receive either intercostal nerve blocks, cryo-ablation combined with intercostal nerve blocks, or serratus plane catheter plus intercostal nerve blocks. The study will enroll a total of 30 patients, who will be monitored throughout their hospital stay and followed up for up to one year post-surgery to assess pain management effectiveness and postoperative complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All adult individuals who undergo an esophagectomy with an intended minimally invasive approach of the chest at Swedish Medical Center-First Hill. These approaches include:

* 3-hole with R video-assisted thoracoscopic surgery (VATS)
* Ivor Lewis R VATS

Exclusion Criteria:

* Age \<18
* Unable to consent
* Additional surgical procedures planned
* Patients with previous thoracic surgery
* Patient with chronic pain on a daily regimen of narcotics
* Non-English speaking
* Contraindications to neuraxial anesthesia (ongoing anticoagulation, anticipated post-operative therapeutic anticoagulation, spinal cord stimulators, anatomic abnormalities preventing epidural placement)

Where it's running

• Swedish Cancer Institute
  Seattle, Washington, United States Recruiting

Study contacts

• Principal investigator: Brian Louie, M.D. — Swedish Cancer Institute
• Study coordinator: Brian Louie, M.D.
• Email: brian.louie@swedish.org
• Phone: (206) 215-6800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.