Ultrasound-guided SPS block versus surgeon intercostal block to prevent chronic pain after thoracoscopic (VATS) surgery
Official title: Evaluation of Serratus Posterior Superior (SPS) Block Versus Surgical Intercostal Blockade in Preventing Chronic Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery (VATS): A Randomized, Prospective, Comparative Study.
Run by Medipol University · NCT07436806 · Data updated 2026-11-12
This trial will test whether an ultrasound-guided Serratus Posterior Superior (SPS) block given before elective VATS reduces chronic post-thoracotomy pain compared with a surgeon-administered intercostal block.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Medipol University Academic / other |
| Locations | 1 site (Istanbul, Bagcilar) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | November 20, 2026 |
| Study ends | December 10, 2026 |
| Registry record updated | March 10, 2026 |
| Trial ID | NCT07436806 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with ASA physical status I–III scheduled for elective unilateral VATS who do not have pre-existing chronic or neuropathic pain, coagulation disorders, prior ipsilateral thoracic surgery, or allergy to local anesthetics.
✕Probably not a fit
Patients with prior same-side thoracic surgery, pre-existing chronic/neuropathic pain, psychiatric conditions affecting pain reporting, coagulation disorders, or local anesthetic allergy would be ineligible and are unlikely to benefit from the interventions in this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery (VATS) at Istanbul Medipol University Hospital will receive either an ultrasound-guided SPS block before surgery or a surgeon-administered intercostal blockade. Primary outcomes include the incidence and severity of chronic post-thoracotomy pain measured at 3, 6, and 12 months, with secondary outcomes of acute pain scores (VAS/NRS) in the first 24 hours, total opioid consumption, and hospital length of stay. The SPS block is performed under ultrasound guidance as a preemptive analgesic, while the comparator is the standard intraoperative intercostal block performed by the surgical team. Safety monitoring includes observation for local anesthetic complications and exclusion of patients with contraindications such as coagulation disorders or local anesthetic allergy.
Why it matters
Potential benefit: If successful, this approach could reduce the number of patients who develop long-term chest pain after VATS and lower early opioid requirements and hospital stay.
How similar studies have gone: Previous work on serratus plane and intercostal blocks has shown improved acute postoperative pain control and reduced opioid use, with mixed but promising signals for preventing chronic pain, while the specific SPS block technique remains relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA physical status I-III. * Scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery (VATS). Exclusion Criteria: * History of allergy to local anesthetics. * Pre-existing chronic pain syndrome or neuropathic pain. * Psychiatric disorders affecting pain assessment. * Coagulation disorders. * Previous thoracic surgery on the same side.
Where it's running
-
Istanbul Medipol University Hospital
Istanbul, Bagcilar, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Bahadir Ciftci, Assoc Prof, MD
- Email: bciftci@medipol.edu.tr
- Phone: +905343736865
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.