Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Ultrasound-guided SPS block versus surgeon intercostal block to prevent chronic pain after thoracoscopic (VATS) surgery

Official title: Evaluation of Serratus Posterior Superior (SPS) Block Versus Surgical Intercostal Blockade in Preventing Chronic Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery (VATS): A Randomized, Prospective, Comparative Study.

Run by Medipol University · NCT07436806 · Data updated 2026-11-12

This trial will test whether an ultrasound-guided Serratus Posterior Superior (SPS) block given before elective VATS reduces chronic post-thoracotomy pain compared with a surgeon-administered intercostal block.

More Neuropathic Pain trials

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment40 (estimated)
SponsorMedipol University
Academic / other
Locations1 site (Istanbul, Bagcilar)
StatusRecruiting
StartedMarch 1, 2026
Main results expectedNovember 20, 2026
Study endsDecember 10, 2026
Registry record updatedMarch 10, 2026
Trial IDNCT07436806 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with ASA physical status I–III scheduled for elective unilateral VATS who do not have pre-existing chronic or neuropathic pain, coagulation disorders, prior ipsilateral thoracic surgery, or allergy to local anesthetics.

Probably not a fit

Patients with prior same-side thoracic surgery, pre-existing chronic/neuropathic pain, psychiatric conditions affecting pain reporting, coagulation disorders, or local anesthetic allergy would be ineligible and are unlikely to benefit from the interventions in this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery (VATS) at Istanbul Medipol University Hospital will receive either an ultrasound-guided SPS block before surgery or a surgeon-administered intercostal blockade. Primary outcomes include the incidence and severity of chronic post-thoracotomy pain measured at 3, 6, and 12 months, with secondary outcomes of acute pain scores (VAS/NRS) in the first 24 hours, total opioid consumption, and hospital length of stay. The SPS block is performed under ultrasound guidance as a preemptive analgesic, while the comparator is the standard intraoperative intercostal block performed by the surgical team. Safety monitoring includes observation for local anesthetic complications and exclusion of patients with contraindications such as coagulation disorders or local anesthetic allergy.

Why it matters

Potential benefit: If successful, this approach could reduce the number of patients who develop long-term chest pain after VATS and lower early opioid requirements and hospital stay.

How similar studies have gone: Previous work on serratus plane and intercostal blocks has shown improved acute postoperative pain control and reduced opioid use, with mixed but promising signals for preventing chronic pain, while the specific SPS block technique remains relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA physical status I-III.
* Scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery (VATS).

Exclusion Criteria:

* History of allergy to local anesthetics.
* Pre-existing chronic pain syndrome or neuropathic pain.
* Psychiatric disorders affecting pain assessment.
* Coagulation disorders.
* Previous thoracic surgery on the same side.

Where it's running

  • Istanbul Medipol University Hospital
    Istanbul, Bagcilar, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.