Using ketorolac for pain relief in lower limb surgeries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of intravenous ketorolac as a regional analgesic in patients undergoing elective unilateral lower limb orthopedic surgeries with spinal anesthesia. Participants will be randomly assigned to receive either 30 mg of ketorolac administered intravenously after tourniquet inflation or 30 mg administered 10 minutes prior to tourniquet application. The primary outcome is to assess the duration of postoperative analgesia provided by this method compared to standard analgesic protocols. All patients will also receive standard postoperative analgesia with paracetamol and diclofenac.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* American Society of Anesthesiologists physical status I or II
* Elective unilateral lower limb orthopedic surgery with tourniquet under spinal anesthesia

Exclusion Criteria:

* Pregnant females
* Body mass index ≥ 35 kg/m2
* Allergy to ketorolac
* Had renal, asthmatic, vascular (Raynaud's syndrome) disease, hematological anemias
* Had any history of gastrointestinal tract inflammation, bleeding, ulceration, or perforation besides
* Edema in the operated limb grade ≥ 3

Where it's running

• Mansoura University Hospitals
  Al Mansurah, Egypt Recruiting

Study contacts

• Study coordinator: Maha AboZeid, MD
• Email: mahazed@mans.edu.eg
• Phone: 02-01019216192

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.