Rectus Sheath Block technique comparison in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 2, randomized, blinded, cross-over style investigation compares transverse versus longitudinal ultrasound guidance for bilateral rectus sheath blocks using lidocaine with epinephrine in healthy-appearing adults. Each participant receives blocks on both sides at a supraumbilical level, with one side using the transverse approach and the other side using the longitudinal approach; the order is randomized. Real-time ultrasound assessment measures spread within the posterior rectus sheath, and dermatomal coverage is mapped at baseline and 60 minutes post-block. The study aims to characterize the distribution and sensory effect of each technique under standardized conditions to inform potential improvements in regional analgesia for midline abdominal wall procedures.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. Ability to provide written informed consent
2. Ability and willingness to comply with the study procedures and duration requirements
3. ASA physical status 1 or 2
4. Age ≥ 18 years
5. Weight \> 60kg

Exclusion criteria:

1. BMI \> 40kg.m-2
2. Use of analgesics within 24 hours before the procedure
3. History of abdominal trauma or surgery
4. Abdominal deformities or abnormalities that may prevent proper block performance
5. Abdominal tattoos in the supraumbilical area
6. Systemic neuromuscular disease
7. Contraindications to regional anesthesia (e.g., infection, allergy)
8. Structures are unable to be visualized by ultrasound
9. Pregnancy
10. Other known health conditions that would affect the participant's ability to successfully complete the study

Where it's running

• Duke University Medical Center
  Durham, North Carolina, United States Recruiting

Study contacts

• Study coordinator: David MacLeod, MBBS
• Email: david.macleod@duke.edu
• Phone: 9198123201

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.