Condition

Post-traumatic Stress Disorder (PTSD) clinical trials and research

• 44Clinical trials
• 14Countries

Newest Post-traumatic Stress Disorder (PTSD) clinical trials

All recruiting trials (44)

• Emotional dysregulation in adolescents with complex trauma traits

  Researchers will observe teens to see how emotional dysregulation shows up in CPTSD and how it differs from BPD and PTSD.

  Recruiting University Hospital, Strasbourg, France · Strasbourg, Grand Est · NCT07794332

• Grappling with Trauma: BJJ for First Responders

  This program tests whether eight weeks of Brazilian Jiu-Jitsu can be tied to changes in trauma-related symptoms for first responders who prefer movement-based activities over traditional mental health services.

  Recruiting Sam Houston State University · Conroe, Texas · NCT07783516

• Eye Movement Intervention with Different Memory Reactivation Procedures for Intrusive Traumatic Memories

  This online trial tests whether combining eye movements with different memory reactivation tasks can reduce intrusive trauma memories in people with PTSD.

  Recruiting Shaanxi Normal University · Xi'an, Shaanxi · NCT07767396

• Trauma-informed Psilocybin-assisted psychotherapy for PTSD

  This study tests whether adding psilocybin to trauma-focused psychotherapy helps people with PTSD see if the approach is safe and tolerable and whether symptoms improve.

  Recruiting Early Phase 1 Tel-Aviv Sourasky Medical Center · Tel Aviv · NCT07737054

• Psilocybin with Structured Integrated Reframing Therapy for trauma-related MDD and PTSD

  This trial tests whether psilocybin therapy, alone or with Structured Integrated Reframing Therapy (SIRT), helps people with trauma-related major depressive disorder who are already on a stable antidepressant.

  Recruiting Phase 3 Khyber Medical University Peshawar · Islamabad, Capital and 2 other locations · NCT07703722

• Faster brain stimulation for PTSD and depression

  This pilot study tests a quicker brain stimulation schedule (accelerated iTBS) to see if it’s doable, safe, and tolerable for adults with PTSD and major depression.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07682207

• Sleep effects of stellate ganglion block in military personnel undergoing prolonged exposure therapy for PTSD

  This study tests how a stellate ganglion block affects sleep in active duty service members and veterans with PTSD who are receiving prolonged exposure therapy.

  Recruiting at 2 sites The University of Texas Health Science Center at San Antonio · Killeen, Texas and 1 other locations · NCT07667309

• Temporal Interference stimulation for PTSD symptom relief

  This study tests whether Temporal Interference stimulation can help reduce PTSD symptoms in adults with PTSD, using twice-daily sessions over a week and follow-up for up to 3 months.

  Recruiting Shanghai Mental Health Center · Shanghai · NCT07644338

• Non-invasive vagus nerve stimulation (gammaCore) for PTSD

  This study will test whether the handheld gammaCore device, which delivers mild electrical stimulation to the vagus nerve through the neck, can help adults with PTSD reduce their symptoms.

  Recruiting Acacia Clinics · Sunnyvale, California · NCT07523685

• Non-invasive vagus nerve stimulation (gammaCore) for PTSD

  This study will test whether the handheld gammaCore device, which delivers mild electrical stimulation to the vagus nerve through the neck, can help adults with PTSD reduce their symptoms.

  Recruiting Acacia Clinics · Sunnyvale, California · NCT07523685

• Non-invasive vagus nerve stimulation (gammaCore) for PTSD

  This study will test whether the handheld gammaCore device, which delivers mild electrical stimulation to the vagus nerve through the neck, can help adults with PTSD reduce their symptoms.

  Recruiting Acacia Clinics · Sunnyvale, California · NCT07523685

• Digital cue-based technique with eye movements for intrusive memories after trauma

  This online study tests a light, non- distressing intervention using visual cues and eye movements to see if it reduces frequent intrusive memories in people with PTSD.

  Recruiting Shaanxi Normal University · Xi'an, Shaanxi · NCT07523360

• Tetris-backed intervention after memory reactivation to help with intrusive memories

  This study tests whether briefly reactivating trauma memories and then playing Tetris can reduce intrusive memories in people with PTSD.

  Recruiting Shaanxi Normal University · Xi'an, Shaanxi · NCT07495917

• Imaging PDE4B in people with PTSD or Alcohol Use Disorder using [18F]PF974

  This study tests whether a PET tracer can image PDE4B in adults with PTSD or alcohol use disorder to better understand brain targets related to these conditions.

  Recruiting Yale University · New Haven, Connecticut · NCT07488819

• Digital stepped-care mindfulness program for emotional disorders

  This project tests whether adding an online mindfulness program to usual care helps adults (18–65) with depression, anxiety, OCD, or PTSD recover faster and stay well longer.

  Recruiting Peking University · Beijing · NCT07458100

• EMDR group program with optional individual EMDR for people with cancer

  This project will try EMDR group therapy plus optional individual EMDR to reduce PTSD symptoms and psychological distress in people diagnosed with cancer.

  Recruiting Università Cattolica di Milano · Milan · NCT07447089

• PTSD treatment delivered by your primary care nurse

  This will test whether nurses trained to deliver a short, four-session trauma therapy can help primary care patients who develop PTSD after a recent life-threatening heart or stroke event.

  Recruiting at 2 sites Rush University Medical Center · Chicago, Illinois and 1 other locations · NCT07430657

• Blended trauma-focused CBT with compassion for adolescents with PTSD

  This trial will test whether a blended program combining an app and face-to-face trauma-focused CBT with added compassion elements helps adolescents (12–17) with PTSD compared with standard TF-CBT.

  Recruiting Umeå University · Umeå · NCT07407946

• TMS for persistent PTSD in 12–20-year-olds

  This project will test whether transcranial magnetic stimulation (TMS) helps 12–20-year-olds who still have PTSD symptoms after completing trauma-focused therapy.

  Recruiting The University of Texas Health Science Center at San Antonio · San Antonio, Texas · NCT07401225

• Building Ukraine's strength in PTSD treatment

  This project will try the Reconsolidation of Traumatic Memories (RTM) protocol alongside standard PTSD treatments to see if it reduces symptoms in adults with PTSD living in Ukraine.

  Recruiting at 2 sites University of Luxembourg · Kyiv and 1 other locations · NCT07318181

• Building Ukraine's strength in PTSD treatment

  This project will try the Reconsolidation of Traumatic Memories (RTM) protocol alongside standard PTSD treatments to see if it reduces symptoms in adults with PTSD living in Ukraine.

  Recruiting at 2 sites University of Luxembourg · Kyiv and 1 other locations · NCT07318181

• Remote brain training to improve thinking and daily life in adults with PTSD

  This project will test whether a remote computer-based brain training program helps adults with PTSD improve memory, attention, and everyday functioning compared with regular computer games.

  Recruiting Université du Québec a Montréal · Montreal, Quebec · NCT07309302

• Mind-body skills groups for war-related trauma in Gaza adolescents

  This study will try group mind-body skills to see if they reduce PTSD symptoms and emotional and behavioral problems in 11–17-year-olds living in Gaza who experienced war trauma.

  Recruiting The Center for Mind-Body Medicine · Deir al-Balah · NCT07302984

• Targeted accelerated transcranial magnetic stimulation for PTSD

  This trial will test whether short, imaging-guided accelerated transcranial magnetic stimulation (aTMS) can quickly reduce PTSD symptoms in adults with moderate-to-severe PTSD.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT07245641

• Child-friendly RTM therapy to reduce PTSD symptoms

  This project will test whether a child-friendly Reconsolidation of Traumatic Memories protocol (RTM-C) can safely reduce PTSD symptoms in children aged 6–14 who have experienced trauma.

  Recruiting Global Institute for Mental Health Innovations, Networking and Development a.s.b.l. · Kyiv · NCT07185126

• Short videos sent by text to support teens and young adults with PTSD

  This project will test whether brief informational videos delivered by text messages can help people aged 15–25 manage PTSD symptoms.

  Recruiting IWK Health Centre · Halifax, Nova Scotia · NCT07165782

• Home-based brain stimulation plus intensive prolonged exposure for chronic pain and PTSD

  This trial will see if adding home-based transcranial direct current stimulation (tDCS) to an intensive, telemedicine-delivered prolonged exposure program helps people with chronic musculoskeletal pain and PTSD reduce symptoms and improve satisfaction compared with sham stimulation.

  Recruiting The University of Texas Health Science Center, Houston · Charleston, South Carolina and 1 other locations · NCT07116109

• Stepped care to improve MOUD retention for women with OUD, PTSD, and IPV history

  This study tests whether a stepped care program combining Present-Centered Therapy and HOPE can help women on medication for opioid use disorder who experienced intimate partner violence stay in treatment longer and reduce PTSD-related problems.

  Recruiting at 2 sites Yale University · Bridgeport, Connecticut and 2 other locations · NCT07115030

• PTSD in French military personnel: Biopsychosocial factors and how security cues affect emotional contagion

  This study tries to understand PTSD and emotional contagion in French military personnel and explores how security-related cues might influence emotional responses.

  Recruiting Direction Centrale du Service de Santé des Armées · Brétigny-sur-Orge · NCT06996275

• Long-term follow-up of children exposed to trauma

  This study looks at children and teens who experienced trauma to see how many still have PTSD or develop new symptoms a year later, while also translating a trauma screening tool into Turkish.

  Recruiting Istanbul University · Istanbul, Fatih · NCT06975852

• Trauma-Focused Therapy for Refugee Minors with PTSD in Greece

  This study is testing if a special therapy for trauma can help unaccompanied refugee teens in Greece with PTSD feel better compared to the usual treatment they receive.

  Recruiting Panteion University · Athens · NCT06975280

• Using Hexadecanal to enhance therapy for PTSD

  This study is testing if adding a special odor called Hexadecanal to therapy can help people with PTSD feel better compared to just the therapy alone.

  Recruiting Tel Aviv University · Tel Aviv · NCT06968312

• Shared decision making to pick PTSD therapy for active duty military

  This project will try shared decision making to match active duty service members with one of three PTSD therapies (Prolonged Exposure, Cognitive Processing Therapy, or Written Exposure Therapy) and either daily or weekly sessions to see if that improves treatment start, completion, and symptom reduction.

  Recruiting at 2 sites The University of Texas Health Science Center at San Antonio · Fort Hood, Texas and 1 other locations · NCT06953687

• Assessing Complex PTSD in Trauma-Exposed Children and Adolescents

  This study is trying to see how common Complex PTSD and PTSD are in children and teens who have experienced trauma, while also working to translate a questionnaire for kids into Turkish.

  Recruiting Istanbul University · Istanbul, Fatih · NCT06918899

• Ketamine during orthopedic trauma surgery to reduce pain, opioid use, and improve mood

  This study will try a single dose of ketamine during surgery to see if it lowers pain and opioid needs and improves depression and PTSD symptoms in adults having major orthopedic trauma surgery.

  Recruiting at 2 sites Phase 4 Texas Tech University Health Sciences Center · Lubbock, Texas and 1 other locations · NCT06903819

• Playing Tetris to improve mental health in migrants

  This study is testing if playing Tetris can help immigrants who have applied for asylum feel less anxious and depressed and prevent PTSD.

  Recruiting Tilburg University · The Hague, NL and 1 other locations · NCT06773338

• Comparing two therapies for treating PTSD

  This study is testing which therapy works better for people with PTSD: eye movement desensitization and reprocessing or cognitive therapy, by giving 270 participants up to 24 weekly sessions of one of the two treatments.

  Recruiting Vestre Viken Hospital Trust · Drammen, Akershus · NCT06691347

• Suvorexant for insomnia in people with alcohol use disorder and PTSD

  This study will test whether suvorexant can reduce insomnia in adults 21–65 who have moderate-to-severe alcohol use disorder and PTSD symptoms.

  Recruiting Phase 2 Pharmacotherapies for Alcohol and Substance Use Disorders Alliance · Los Angeles, California and 1 other locations · NCT06679062

• NightWare for reducing nightmares and supporting heart health in Veterans with PTSD

  This trial will test whether a prescription wrist-wearable app called NightWare can reduce PTSD-related nightmares and improve sleep and cardiovascular health in Veterans.

  Recruiting VA Office of Research and Development · Aurora, Colorado · NCT06419959

• Sublingual dexmedetomidine (BXCL501) for people with alcohol use disorder and PTSD

  This outpatient study will try a daily sublingual dexmedetomidine film (BXCL501) for up to 28 days in adults with alcohol use disorder who also have PTSD or a qualifying trauma to see if it is safe and shows early signs of benefit.

  Recruiting Phase 1 Pharmacotherapies for Alcohol and Substance Use Disorders Alliance · West Haven, Connecticut · NCT06335407

• Using oxytocin to enhance couples therapy for veterans with PTSD

  This study is testing if adding a nasal spray of oxytocin to couples therapy can help veterans with PTSD and their partners feel better and improve their relationship.

  Recruiting Phase 2 VA Office of Research and Development · San Diego, California · NCT06194851

• Mindfulness training for Veterans with PTSD, depression, and anxiety

  This study is testing whether mindfulness training can help Veterans with PTSD, depression, and anxiety feel better compared to a regular problem-solving class.

  Recruiting at 3 sites VA Office of Research and Development · Phoenix, Arizona and 3 other locations · NCT06162741

• Evaluating treatments for suicidal veterans with PTSD

  This study is testing a new combined therapy for veterans with PTSD who are at risk of suicide to see if it works better than the usual treatment they currently receive.

  Recruiting at 4 sites VA Office of Research and Development · Minneapolis, Minnesota and 3 other locations · NCT05974631

• Psychotherapy for people with HIV and PTSD

  This study is testing a new type of therapy for people living with HIV and PTSD to see if it helps them feel better and improve their health.

  Recruiting Montefiore Medical Center · The Bronx, New York · NCT05929911

Related topics

Quick answers

How many Post-traumatic Stress Disorder (PTSD) clinical trials are recruiting right now?

44, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in United States (20 trials), China (5 trials), Ukraine (3 trials), Canada (3 trials), Israel (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 1, Early Phase 1: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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