Trauma-Focused Therapy for Refugee Minors with PTSD in Greece

Implementation, Cultural Adaptation, and Efficacy Evaluation of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for Unaccompanied Refugee Minors in Greece

Not applicable Interventional Panteion University · NCT06975280

This study is testing if a special therapy for trauma can help unaccompanied refugee teens in Greece with PTSD feel better compared to the usual treatment they receive.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages15 Years to 18 Years
SexAll
SponsorPanteion University Academic / other
Locations1 site (Athens)
Trial IDNCT06975280 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial evaluates the effectiveness of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) compared to Treatment-as-Usual (TAU) for unaccompanied refugee minors aged 15-18 in Greece who are experiencing PTSD. Participants will be randomly assigned to either the TF-CBT intervention group or the TAU control group, with assessments conducted at baseline, post-intervention, and three months later using standardized psychometric tools. The study aims to adapt TF-CBT to the Greek cultural context and provide guidelines for its implementation, addressing the urgent need for effective mental health interventions for this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates are unaccompanied minors aged 15-18 residing in accommodation centers or Supported Independent Living programs in Greece with a diagnosis of PTSD.

Not a fit: Patients with intellectual disabilities, acute suicidality, or significant comorbid psychiatric disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly reduce PTSD symptoms and improve overall mental health for unaccompanied refugee minors.

How similar studies have performed: While TF-CBT has been effective in other populations, this is the first randomized controlled trial assessing its efficacy specifically for unaccompanied refugee minors in Greece.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be unaccompanied upon arrival in Greece and aged between 15-18 years old.
* Being diagnosed with PTSD based on DSM-5 criteria. Young refugees with post-traumatic stress symptoms (PTSS), as delineated by high or moderate trauma-related distress in the Child and Adolescent Trauma Screen (CATS), will also be eligible to participate in the study.
* Reside in an accommodation center or SIL program for UAMs in Greece.
* Have a stable living arrangement for at least 2-3 weeks prior to the intervention.
* Not be expected to relocate within the 2-3 months following the start of the intervention.

Exclusion Criteria:

* a diagnosed intellectual disability (IQ \< 70) or another developmental disorder
* acute suicidality or life-threatening self-harm behavior
* significant risk of harm to others
* comorbidity with bipolar disorder or a psychotic disorder
* substance abuse.

Where this trial is running

Athens

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post-Traumatic Stress DisorderDepressive SymptomsAnxiety SymptomsSomatic SymptomsEmotional and Behavioral DifficultiesUnaccompanied minorsRefugee adolescentsTrauma-Focused Cognitive Behavioral Therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.