Psychotherapy for people with HIV and PTSD

Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD

NA · Montefiore Medical Center · NCT05929911

This study is testing a new type of therapy for people living with HIV and PTSD to see if it helps them feel better and improve their health.

Quick facts

PhaseNA
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorMontefiore Medical Center (other)
Locations1 site (The Bronx, New York)
Trial IDNCT05929911 on ClinicalTrials.gov

What this trial studies

This pilot study focuses on individuals living with HIV who also have post-traumatic stress disorder (PTSD). It adapts a non-exposure based psychotherapy that emphasizes emotional reflection and relationship dynamics to address the unique needs of this population. The study aims to assess the acceptability and effectiveness of this treatment while exploring the connections between HIV-related health factors and PTSD. By understanding these relationships, the research seeks to improve health outcomes for participants.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with PTSD and HIV who have stable psychiatric medication management.

Not a fit: Patients with acute suicidality, psychosis, or unstable medical conditions unrelated to HIV may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve the mental health and overall well-being of patients living with HIV and PTSD.

How similar studies have performed: While there is limited research specifically on this approach for PLWH, similar psychotherapeutic interventions have shown promise in treating PTSD in other populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25
* HIV diagnosis (by medical records or HIV testing)
* Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment

Exclusion Criteria:

* Psychosis
* Bipolar I
* Acute suicidality
* Current substance use disorder
* Organic mental syndrome or intellectual disability
* Unstable non-HIV medical conditions

Where this trial is running

The Bronx, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Post Traumatic Stress Disorder, HIV, PTSD, psychotherapy, trauma

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.