Psychotherapy for people with HIV and PTSD
Official title: Pilot Feasibility Proposal to Adapt Trauma-focused Psychodynamic Psychotherapy (TFPP) for PLWH and PTSD
Run by Montefiore Medical Center · NCT05929911 · Data updated 2026-11-12
This study is testing a new type of therapy for people living with HIV and PTSD to see if it helps them feel better and improve their health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Montefiore Medical Center Academic / other |
| Locations | 1 site (The Bronx, New York) |
| Status | Recruiting |
| Started | April 26, 2024 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT05929911 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with PTSD and HIV who have stable psychiatric medication management.
✕Probably not a fit
Patients with acute suicidality, psychosis, or unstable medical conditions unrelated to HIV may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study focuses on individuals living with HIV who also have post-traumatic stress disorder (PTSD). It adapts a non-exposure based psychotherapy that emphasizes emotional reflection and relationship dynamics to address the unique needs of this population. The study aims to assess the acceptability and effectiveness of this treatment while exploring the connections between HIV-related health factors and PTSD. By understanding these relationships, the research seeks to improve health outcomes for participants.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the mental health and overall well-being of patients living with HIV and PTSD.
How similar studies have gone: While there is limited research specifically on this approach for PLWH, similar psychotherapeutic interventions have shown promise in treating PTSD in other populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of DSM-5 defined PTSD, per the Clinician Administered PTSD Scale \& CAPS-5 total severity score greater than or equal to 25 * HIV diagnosis (by medical records or HIV testing) * Stable psychiatric/psychotropic medication for \>=2 months and ongoing during treatment Exclusion Criteria: * Psychosis * Bipolar I * Acute suicidality * Current substance use disorder * Organic mental syndrome or intellectual disability * Unstable non-HIV medical conditions
Where it's running
-
Albert Einstein College of Medicine
The Bronx, New York, United States Recruiting
Study contacts
- Principal investigator: Barbara Milrod, MD — Montefiore Medical Center
- Study coordinator: John R Keefe, PhD
- Email: john.keefe@einsteinmed.edu
- Phone: 703-981-7184
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.