Tetris-backed intervention after memory reactivation to help with intrusive memories
Official title: A Tetris Intervention Following Subliminal Reactivation for Reducing Intrusive Memories in Trauma-exposed Individuals: a Randomized Controlled Trial
Run by Shaanxi Normal University · NCT07495917 · Data updated 2026-11-12
This study tests whether briefly reactivating trauma memories and then playing Tetris can reduce intrusive memories in people with PTSD.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 50 Years |
| Sex | All |
| Enrollment | 106 (estimated) |
| Sponsor | Shaanxi Normal University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Status | Recruiting |
| Started | April 10, 2026 |
| Main results expected | June 10, 2028 |
| Study ends | July 30, 2028 |
| Registry record updated | September 2, 2026 |
| Trial ID | NCT07495917 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with PTSD who experience three or more intrusive memories per week and have reliable internet access and a personal computer.
✕Probably not a fit
Individuals with fewer than three intrusive memories per week or with certain comorbid conditions may not experience benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized trial, participants with PTSD who experience at least three intrusive memories per week are assigned to either a memory-reactivation plus Tetris task or a control condition with only the visuospatial task. The intervention begins with trauma-related memory reactivation, followed by a music interval and a visuospatial interference task using Tetris; the control arm performs only the visuospatial task. Intrusive memories and related symptoms are tracked during follow-up to see if the combined approach offers added benefit. Participants provide trauma-related images for the reactivation procedure, and study procedures are conducted online with computer access. The trial is conducted at Shaanxi Normal University in Xi'an, China, led by the School of Psychology.
Why it matters
Potential benefit: If successful, the intervention could provide a non-pharmacologic option to reduce intrusive memories for people with PTSD.
How similar studies have gone: Previous small studies in healthy individuals suggested the approach may reduce intrusive memories, but this randomized trial tests effectiveness in a clinical PTSD population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Meet DSM-5 PTSD Criterion A (eg, exposure to actual or threatened death). Have experienced one or more traumatic events. 2. Experienced three or more intrusive memories during the baseline week. 3. Have internet access and have access to a personal computer. 4. Be willing to provide consent and able to complete study procedures and be contacted by the study team. Exclusion Criteria: 1. Have fewer than three intrusive memories during the baseline week. 2. A current diagnosis of schizophrenia, obsessive-compulsive disorder (OCD), a severe personality disorder judged to interfere with treatment adherence, or acute suicidal behavior. 3. Have severe substance dependence.
Where it's running
-
School of Psychology, Shaanxi Normal University
Xi'an, Shaanxi, China Recruiting
Study contacts
- Study coordinator: Zhu Zijian
- Email: zhuzijian0203@snnu.edu.cn
- Phone: +86 13572494696
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.