Clinical trial Recruiting at 1 site Interventional Ages 18 to 50

Tetris-backed intervention after memory reactivation to help with intrusive memories

Official title: A Tetris Intervention Following Subliminal Reactivation for Reducing Intrusive Memories in Trauma-exposed Individuals: a Randomized Controlled Trial

Run by Shaanxi Normal University · NCT07495917 · Data updated 2026-11-12

This study tests whether briefly reactivating trauma memories and then playing Tetris can reduce intrusive memories in people with PTSD.

Quick facts

Study typeInterventional
Ages18 Years to 50 Years
SexAll
Enrollment106 (estimated)
SponsorShaanxi Normal University
Academic / other
Locations1 site (Xi'an, Shaanxi)
StatusRecruiting
StartedApril 10, 2026
Main results expectedJune 10, 2028
Study endsJuly 30, 2028
Registry record updatedSeptember 2, 2026
Trial IDNCT07495917 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with PTSD who experience three or more intrusive memories per week and have reliable internet access and a personal computer.

Probably not a fit

Individuals with fewer than three intrusive memories per week or with certain comorbid conditions may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized trial, participants with PTSD who experience at least three intrusive memories per week are assigned to either a memory-reactivation plus Tetris task or a control condition with only the visuospatial task. The intervention begins with trauma-related memory reactivation, followed by a music interval and a visuospatial interference task using Tetris; the control arm performs only the visuospatial task. Intrusive memories and related symptoms are tracked during follow-up to see if the combined approach offers added benefit. Participants provide trauma-related images for the reactivation procedure, and study procedures are conducted online with computer access. The trial is conducted at Shaanxi Normal University in Xi'an, China, led by the School of Psychology.

Why it matters

Potential benefit: If successful, the intervention could provide a non-pharmacologic option to reduce intrusive memories for people with PTSD.

How similar studies have gone: Previous small studies in healthy individuals suggested the approach may reduce intrusive memories, but this randomized trial tests effectiveness in a clinical PTSD population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Meet DSM-5 PTSD Criterion A (eg, exposure to actual or threatened death). Have experienced one or more traumatic events.
2. Experienced three or more intrusive memories during the baseline week.
3. Have internet access and have access to a personal computer.
4. Be willing to provide consent and able to complete study procedures and be contacted by the study team.

Exclusion Criteria:

1. Have fewer than three intrusive memories during the baseline week.
2. A current diagnosis of schizophrenia, obsessive-compulsive disorder (OCD), a severe personality disorder judged to interfere with treatment adherence, or acute suicidal behavior.
3. Have severe substance dependence.

Where it's running

  • School of Psychology, Shaanxi Normal University
    Xi'an, Shaanxi, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.