Clinical trial Recruiting at 2 sites Interventional Ages 18 to 65

Building Ukraine's strength in PTSD treatment

Official title: Fostering Ukraine's Capacity in the Delivery and Research of Innovative Evidence-based PTSD Treatment

Run by University of Luxembourg · NCT07318181 · Data updated 2026-11-12

This project will try the Reconsolidation of Traumatic Memories (RTM) protocol alongside standard PTSD treatments to see if it reduces symptoms in adults with PTSD living in Ukraine.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment120 (estimated)
SponsorUniversity of Luxembourg
Academic / other
Locations2 sites (Kyiv and 1 other locations)
StatusRecruiting
StartedJanuary 1, 2026
Main results expectedNovember 2027
Study endsMay 2028
Registry record updatedJanuary 15, 2026
Trial IDNCT07318181 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–65 who are residents of Ukraine with a DSM-5-TR or ICD-11 diagnosis of PTSD or clinically significant PTSD symptoms are the intended participants.

Probably not a fit

People with acute comorbid psychiatric disorders, severe cognitive impairment, inability to consent, or those already receiving other parallel PTSD treatments may not benefit from or be eligible for participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Lux4UA project implements the short RTM protocol and compares it with guideline treatments (TF-CBT, EMDR, and SSRI medication) at clinical sites in Kyiv. Trained clinicians deliver RTM in typically three to five sessions, and patients are followed with standardized measures such as the PCL-5 to track symptom change, function, and dropout. The project includes therapist training and capacity-building to support delivery and research of evidence-based trauma care in the Ukrainian humanitarian context. Findings will inform whether RTM is a feasible, faster alternative to longer trauma-focused therapies for civilians, displaced persons, and military personnel.

Why it matters

Potential benefit: If successful, RTM could provide faster relief from PTSD symptoms with fewer sessions and less need to retell traumatic events.

How similar studies have gone: Prior small randomized and clinical reports have shown promising, often rapid symptom reductions with RTM in a few sessions, but large-scale replication in diverse settings is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. being adults 18-65 years,
2. having a diagnosis of PTSD determined by DSM-5-TR or ICD-11 and/or
3. having PTSD symptoms causing clinically significant distress or impact on social, occupational, or other areas of functioning, as defined by the PTSD Checklist PCL-5,
4. being a resident of Ukraine.

Exclusion Criteria:

1. having any other acute comorbid mental health conditions,
2. receiving any other parallel PTSD treatment,
3. being unable to provide informed consent, having severe cognitive impairment, or being otherwise unlikely to adhere to study procedures.

Where it's running

  • National Psychological Association of Ukraine
    Kyiv, Ukraine
    Recruiting
  • Veteran Mental Health and Rehabilitation Center 'Forest Glade' Ministry of Health of Ukraine
    Kyiv, Ukraine
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.