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Primary Peritoneal Carcinoma clinical trials and research

• 21Clinical trials
• 1New in 30 days
• 11Countries

Newest Primary Peritoneal Carcinoma clinical trials

All recruiting trials (21)

• KRAS Inhibitor ETX-929 in advanced solid tumors

  This trial tests ETX-929, alone or with cetuximab, in people whose cancers have KRAS mutations and have progressed after prior therapy.

  Recruiting Phase 1/2 Ensem Therapeutics · Fairfax, Virginia · NCT07912593

• Dual-target CAR-NK Cells for Peritoneal Cancers of the Ovary, Fallopian Tube, or Pseudoperitoneal Disease

  This trial tests a dual-target CAR-NK cell therapy for people with recurrent or hard-to-treat epithelial ovarian, fallopian tube, or primary peritoneal cancer who express two or more specific tumor markers.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07617753

• IGFBP-2 vaccine after platinum to slow ovarian cancer recurrence

  This study tests whether giving an IGFBP-2 vaccine after one carboplatin dose can help prevent progression of ovarian, fallopian tube, or primary peritoneal cancer that has shown serologic recurrence.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT07495124

• Dual-target CAR-NK therapy for recurrent ovarian, fallopian tube, or primary peritoneal cancer

  This trial tests whether dual-target CAR‑NK cells can shrink tumors in people with recurrent or refractory epithelial ovarian, fallopian tube, or primary peritoneal cancer whose tumors express at least two of MSLN, FRα, or MUC16.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07480954

• In-home cancer treatment with remote specialist support for patients in the Florida Panhandle

  This program will try giving standard cancer treatments at home to people living in the Florida Panhandle and nearby areas to see if they prefer it and have better treatment satisfaction.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT07285044

• Personalized timing for interval debulking surgery in advanced ovarian cancer

  This study will test whether timing interval debulking surgery based on the CA125 drop (KELIM) after neoadjuvant chemotherapy helps people with advanced ovarian, fallopian tube, or primary peritoneal cancer have better surgical outcomes than usual care.

  Recruiting Phase 2 The University of Hong Kong · Guangzhou and 5 other locations · NCT07023484

• IMNN-001 combined with standard chemotherapy for newly diagnosed advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer

  This trial tests whether adding IMNN-001 (an intraperitoneal IL-12 plasmid therapy) to standard paclitaxel/carboplatin chemotherapy helps people with newly diagnosed advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer.

  Recruiting at 10 sites Phase 3 Imunon · Orlando, Florida and 9 other locations · NCT06915025

• Testing PHST001 for advanced solid tumors

  This study is testing a new treatment called PHST001 to see if it is safe and effective for people with advanced solid tumors that haven't responded to other therapies.

  Recruiting at 20 sites Phase 1 Pheast Therapeutics · Beverly Hills, California and 19 other locations · NCT06840886

• Using cryocompression and cilostazol to prevent nerve damage from chemotherapy in women with gynecological cancers

  This study is testing if using cryocompression therapy alone or with a medication called cilostazol can help prevent nerve damage from chemotherapy in women with gynecological cancers.

  Recruiting Phase 2 Emory University · Atlanta, Georgia and 2 other locations · NCT06492070

• Immune cell therapy for recurrent ovarian cancer

  This study is testing a new immune cell therapy called 27T51 to see if it can help women with recurrent ovarian cancer feel better and fight their disease.

  Recruiting at 5 sites Phase 1 Regeneron Pharmaceuticals · Boston, Massachusetts and 4 other locations · NCT06469281

• Treatment for recurrent ovarian cancer with HER2 expression

  This study is testing a new combination of treatments for women with recurrent ovarian cancer that has a specific protein called HER2 to see if it helps them feel better and live longer.

  Recruiting Phase 2 Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT06420973

• Evaluating Sovilnesib for Ovarian Cancer Treatment

  This study is testing a new drug called sovilnesib to see if it can safely help people with a tough type of ovarian cancer that doesn't respond to standard treatments.

  Recruiting at 4 sites Phase 1 Volastra Therapeutics, Inc. · Birmingham, Alabama and 10 other locations · NCT06084416

• Testing Rinatabart Sesutecan for advanced solid tumors

  This study is testing a new drug called Rinatabart Sesutecan to see if it can safely help people with advanced solid tumors, like certain types of ovarian and endometrial cancers.

  Recruiting at 67 sites Phase 1/2 Genmab · Phoenix, Arizona and 66 other locations · NCT05579366

• Comparing 3 vs. 6 cycles of chemotherapy followed by niraparib for advanced ovarian cancer

  This study is testing whether having 3 or 6 cycles of chemotherapy followed by a drug called niraparib can help people with advanced ovarian cancer stay cancer-free longer.

  Recruiting at 31 sites Phase 2 North Eastern German Society of Gynaecological Oncology · Innsbruck and 49 other locations · NCT05460000

• Comparing stress reduction methods to standard care for ovarian cancer patients

  This study is testing if a mix of medications and therapies can help reduce stress in women with advanced ovarian cancer before their surgery, compared to those getting standard care.

  Recruiting at 7 sites Memorial Sloan Kettering Cancer Center · Basking Ridge, New Jersey and 6 other locations · NCT05429970

• Hepato-celiac lymphadenectomy for survival in primary or relapsed ovarian-related cancers

  This trial will try hepato-celiac lymphadenectomy to see if removing hepato-celiac lymph nodes helps adults with advanced or platinum-sensitive relapsed epithelial ovarian, fallopian tube, or primary peritoneal cancer that has spread to those nodes.

  Recruiting Shanghai Gynecologic Oncology Group · Shanghai · NCT05236686

• Combining surgery with targeted therapy for advanced ovarian cancer treatment

  This study is testing the best timing for surgery combined with targeted treatments to see if it helps people with advanced ovarian cancer feel better and live longer.

  Recruiting at 9 sites Phase 2 Shanghai Gynecologic Oncology Group · Foshan and 8 other locations · NCT05200260

• Maintenance therapy for ovarian cancer after chemotherapy

  This study is testing a new treatment called DCVAC/OvCa to see if it can help women with advanced ovarian cancer feel better after their initial chemotherapy.

  Recruiting Phase 2 Peking University Third Hospital · Beijing, Beijing Municipality · NCT04834544

• Surgery and Niraparib for recurrent ovarian cancer

  This study is testing whether surgery followed by chemotherapy and a drug called Niraparib can help people with recurrent ovarian cancer do better than just chemotherapy alone.

  Recruiting Phase 2 Shanghai Gynecologic Oncology Group · Shanghai, Shanghai Municipality and 4 other locations · NCT03983226

• Imaging with a new radioactive tracer for solid tumors

  This study is testing a new imaging method using a special radioactive tracer to see if it can help find tumor cells in patients with solid tumors like ovarian and breast cancers, while also looking at how safe it is and how it relates to certain genetic factors.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT03604315

• Collecting data on patients with low-grade ovarian or peritoneal tumors

  This study is collecting information from around 1600 women with low-grade ovarian or peritoneal tumors to help understand their disease and improve future treatments.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT00488878

Related topics

Quick answers

How many Primary Peritoneal Carcinoma clinical trials are recruiting right now?

21, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (12 trials), China (9 trials), Hong Kong (1 trial), Japan (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 9, Phase 1/2: 4, Phase 1: 4, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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