Identifying biomarkers and treatment strategies for peritoneal surface malignancies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify biomarkers associated with disease recurrence and prognosis in patients with peritoneal surface malignancies (PSM) such as pseudomyxoma peritonei, colorectal carcinoma, ovarian carcinoma, and mesothelioma. The study will optimize patient selection for cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). Utilizing a unique biobank and institutional database, along with novel animal models, the research team will explore various treatment strategies to improve outcomes for patients with limited disease. Approximately 80 patients per year will be included based on their eligibility for CRS-HIPEC.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age \> 18 years
* confirmed diagnosis of peritoneal surface malignancy
* candidate for CRS-HIPEC
* written informed consent

Exclusion Criteria:

* none

Approximately 80 patients per year will be eligible for inclusion, as this is the number of patients that annually receive surgical treatment for PSM.

Where it's running

• The Norwegian Radium Hospital
  Oslo, Norway Recruiting

Study contacts

• Principal investigator: Kjersti Flatmark, MD PhD — Oslo University Hospital
• Study coordinator: Kjersti Flatmark, MD PhD
• Email: Kjersti.Flatmark@rr-research.no
• Phone: +47 22 93 40 00

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.