Evaluating sentinel lymph node biopsy for early-stage ovarian cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study aims to assess the efficacy of sentinel lymph node biopsy (SLNB) in patients with early-stage ovarian cancer by comparing its results to those obtained from systematic lymphadenectomy. Ovarian cancer is a leading cause of gynecologic cancer mortality, and accurate staging is crucial for treatment and prognosis. The study focuses on patients with suspicious adnexal masses, as up to 30% may be upstaged based on final pathology. By potentially reducing the need for extensive lymphadenectomy, the SLNB could minimize associated surgical risks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Must have a suspicious adnexal mass for early stage ovarian cancer

Must be medically and surgically fit enough to perform SLNB and complete the systematic lymphadenectomy.

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Exclusion Criteria:

Ovarian mass with low probability for early stage ovarian cancer.

Medical or surgical contraindications for surgical comprehensive staging.

Metastatic cancers or double primary cancers (metachronous) of ovary

Recurrent ovarian cancer

Preoperative or intraoperative finding of advanced ovarian cancer (FİGO stage III and IV)

Neoadjuvant ovarian cancer

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Where it's running

• Istanbul University
  Istanbul, Turkey, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Mustafa ALBAYRAK, MD
• Email: mustafaalbayrak@icloud.com
• Phone: +90 532 687 10 51

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.