Condition

Obsessive Compulsive Disorder (OCD) clinical trials and research

• 29Clinical trials
• 1NIH research projects
• 11Countries

Newest Obsessive Compulsive Disorder (OCD) clinical trials

All recruiting trials (29)

• Focused ultrasound for mood and anxiety disorders

  This study tests whether repeated low-intensity focused ultrasound using the ATTN201 device can help people with subsyndromal to moderate depression, anxiety, or OCD.

  Recruiting Attune Neurosciences Inc · San Francisco, California and 1 other locations · NCT07851038

• Predicting Treatment Response in Psychiatric Disorders Using Biological Markers

  This study tests whether biological markers can predict which patients with psychiatric conditions will respond to treatment.

  Recruiting Centre Hospitalier St Anne · Paris · NCT07741981

• Safety and feasibility of a next-generation dome helmet for neuromodulation in OCD

  This study tests whether a new focused ultrasound helmet can safely help people with treatment-refractory OCD see if their symptoms improve.

  Recruiting Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07704632

• Bergen Four-Day Treatment for OCD, in Finland

  This trial tests whether the Bergen Four-Day Treatment for OCD can be implemented in Finnish psychiatric care to help people with OCD see if the intensive program works in a real-world setting.

  Recruiting Tampere University Hospital · Tampere · NCT07644130

• Test different deep TMS coils and targets to treat OCD

  This study tests whether different deep TMS coils and brain targets help reduce OCD symptoms in adults with OCD, using a double-blind setup with sham and active stimulation.

  Recruiting Taipei Veterans General Hospital, Taiwan · Taipei · NCT07587112

• Role of theta brain waves in how kids control thoughts and actions

  This study tests whether theta-frequency brain activity can reveal how children with ADHD or OCD, and healthy kids, manage thinking and behavior during tasks.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07566468

• Low-intensity focused ultrasound targeting for OCD

  This pilot will test whether single sessions of low-intensity focused ultrasound (LIFU) aimed at specific subcortical brain targets are safe, feasible, and change symptoms in adults with chronic OCD.

  Recruiting University of Pennsylvania · Philadelphia, Pennsylvania · NCT07558148

• OCD Summer Treatment Program for Icelandic Adolescents

  This program tests a two-week group-based intensive cognitive-behavioral treatment with exposure and response prevention for Icelandic adolescents with OCD and involvement from their parents.

  Recruiting University of Iceland · Reykjavik · NCT07465354

• Stepped care program for anxiety in children and teens

  This program will see if a stepped care approach that starts with parent-focused support and steps up to child therapy can help children and teens (ages 7–17) in Texas with anxiety disorders or OCD.

  Recruiting Baylor College of Medicine · Houston, Texas · NCT07228143

• Lifestyle program to lower heart and metabolic risk in people with obsessive-compulsive disorder

  This program will test whether a group lifestyle intervention helps adults with OCD become more physically active and lower their cardiometabolic risk.

  Recruiting Karolinska Institutet · Huddinge, Stockholm County · NCT07206212

• Accelerated personalized rTMS for treatment‑resistant obsessive‑compulsive disorder

  This study will try a fast, personalized course of repetitive transcranial magnetic stimulation (rTMS) targeting the right inferior frontal cortex to see if it reduces symptoms in adults with treatment‑resistant OCD.

  Recruiting Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University · Shanghai, Shanghai Municipality · NCT07198594

• Helping adults with OCD find and keep employment

  This study will test whether adding Individual Placement and Support (IPS) to standard vocational help helps unemployed adults with OCD who are getting CBT find and maintain competitive work.

  Recruiting New York State Psychiatric Institute · New York, New York · NCT07124780

• Temporal interference stimulation for obsessive-compulsive disorder

  This project will try noninvasive temporal interference brain stimulation in adults with moderate-to-severe OCD to see if stimulating different deep brain targets reduces symptoms compared with sham.

  Recruiting Shanghai Mental Health Center · Shanghai, Shanghai Municipality · NCT07113652

• Effect of Moderate-Intensity Exercise on OCD Symptoms and Cognitive Flexibility

  This study tests whether 20 minutes of moderate-intensity cycling can help adults with OCD feel less distress and urges while improving cognitive flexibility compared with a low-intensity activity.

  Recruiting Yale University · New Haven, Connecticut · NCT07103902

• Brief Cognitive Behaviour Therapy for adolescents with OCD

  This study is testing a short, five-session therapy for teenagers with OCD to see if it can help them feel better and fit into regular mental health services, especially for those who also have autism.

  Recruiting University of Oxford · Reading, Berkshire and 2 other locations · NCT06983301

• Personalized brain stimulation for treating obsessive compulsive disorder

  This study is testing a personalized brain stimulation treatment for obsessive compulsive disorder to see if it works better than a standard version of the same treatment.

  Recruiting Centre for Addiction and Mental Health · Toronto, Ontario · NCT06942559

• Gamified cognitive bias modification for adults with OCD

  This study is testing a fun mobile game designed to help adults with OCD change their thinking patterns to see if it works better than standard treatments or a placebo.

  Recruiting Dokuz Eylul University · Izmir · NCT06941155

• Team-delivered exposure-based CBT for children and teens with anxiety and OCD

  This test tries three ways of delivering team-based exposure-focused CBT—in-person, by telehealth, or a flexible mix—to see which works best for kids and teens (ages 5–18) with anxiety or OCD.

  Recruiting Bradley Hospital · East Providence, Rhode Island · NCT06934525

• Frontopolar tDCS to improve safety learning and extinction in OCD

  This will test whether brief frontopolar transcranial direct current stimulation (tDCS) can help adults with OCD improve extinction learning and safety-signal processing.

  Recruiting Yale University · New Haven, Connecticut · NCT06834217

• Assessing mental health disorders in Hong Kong using a new recall method

  This study is testing a new way to help people in Hong Kong remember important life events to see how many have experienced major depression and thoughts of suicide.

  Recruiting The University of Hong Kong · Hong Kong · NCT06804525

• Personalized neurostimulation for treatment-resistant OCD

  This study is testing a new brain stimulation therapy for people with obsessive-compulsive disorder who haven't found relief from other treatments to see if it can help reduce their symptoms.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT06782867

• Identifying genetic markers for SSRI-induced behavioral activation in youth

  This study is trying to find genetic markers that can help predict which children and teens with depression or anxiety might experience increased energy or restlessness from taking certain antidepressants.

  Recruiting at 2 sites University of Manitoba · Winnipeg, Manitoba and 1 other locations · NCT06763081

• Combining Cognitive Behavioral Therapy with Brain Stimulation for OCD Treatment

  This study is testing if combining a type of therapy called Cognitive Behavioral Therapy with a brain stimulation technique can help people with obsessive-compulsive disorder feel better.

  Recruiting Shanghai Mental Health Center · Shanghai, Shanghai Municipality · NCT06717165

• Using Acceptance and Commitment Therapy to help religious OCD

  This project will try Acceptance and Commitment Therapy (ACT) to see if it helps adults with religiously focused OCD.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06647589

• Investigating brain activity in patients with OCD using deep brain stimulation

  This study is testing how deep brain stimulation can help people with severe OCD by looking at their brain activity and behaviors in different settings.

  Recruiting at 2 sites Baylor College of Medicine · Houston, Texas and 1 other locations · NCT06596447

• Improving functioning in veterans with OCD using therapy

  This study is testing if a special therapy called Exposure and Response Prevention can help veterans with OCD feel better and improve their daily lives compared to a stress management program.

  Recruiting at 19 sites VA Office of Research and Development · East Orange, New Jersey and 18 other locations · NCT05240924

• Personalized deep brain stimulation of the anterior limb of the internal capsule for OCD

  This study tests whether tailoring deep brain stimulation to each person's specific ALIC brain connections can help adults with severe, treatment‑resistant OCD.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT05160129

• A platform for collecting health data on ME/CFS and Long Covid

  This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.

  Recruiting Brain Inflammation Collaborative · Delafield, Wisconsin · NCT04806620

• Deep brain stimulation for severe obsessive-compulsive disorder

  This study is testing if deep brain stimulation can help people with severe obsessive-compulsive disorder who haven't found relief from other treatments.

  Recruiting Northwell Health · Queens, New York · NCT02773082

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating the cholinergic system's role in Obsessive Compulsive Disorder

  This study is looking at how a part of the brain that uses a chemical called acetylcholine might be linked to obsessive-compulsive disorder (OCD) by using mice that show similar behaviors, with the hope of finding new ways to help people with OCD feel better.

  NIH research State University New York Stony Brook · Stony Brook, United States · NIH-11109641

Related topics

Quick answers

How many Obsessive Compulsive Disorder (OCD) clinical trials are recruiting right now?

29, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (14 trials), China (4 trials), Canada (3 trials), France (1 trial), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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