Condition

Lipedema clinical trials and research

• 18Clinical trials
• 1NIH research projects
• 3New in 30 days
• 4Countries

Newest Lipedema clinical trials

All recruiting trials (18)

• Kinesio Taping Added to Standard Care for Women with Lipedema

  This study tests whether adding kinesio taping to usual care helps reduce pain for women with stage II lipedema.

  Recruiting Kanuni Sultan Suleyman Training and Research Hospital · Küçükçekmece, Istanbul · NCT07919574

• Comparison of body composition in lipedema and obesity

  This study tests whether women with lipedema have different segmental body fat and muscle distribution compared with BMI-matched women without lipedema.

  Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Uskudar · NCT07878299

• Comparison of Different Exercise Protocols for Lipedema

  This study tests whether high‑intensity interval training or moderate‑intensity continuous training improves function, strength, and quality of life in adults with lipedema.

  Recruiting Hitit University · Çorum · NCT07873541

• taVNS-enriched rehab for lipedema

  This study tests whether adding transcutaneous auricular vagus nerve stimulation (taVNS) to standard rehabilitation helps people with lipedema reduce symptoms.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07857499

• Manual and self-lymphatic drainage with exercise for lipedema

  This study tests whether manual lymph drainage plus supervised exercise works better than self-lymph drainage plus guided activity for reducing pain and improving function in women with lipedema over six weeks.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803926

• Turkish version of the Duke Activity Status Index in women with lipedema

  This study tests whether the Turkish Duke Activity Status Index accurately and consistently measures functional capacity in women with lipedema.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Eyupsultan · NCT07803913

• Aquatic vs. land-based exercise for lipedema in women

  This trial tests whether supervised pool workouts or equivalent land-based exercise improve walking ability and symptoms more than standard care for women with lipedema.

  Recruiting Cairo University · Giza, Dokki · NCT07756463

• 2-Minute Step Test in Women with Lipedema

  This study tests whether the 2-Minute Step Test can reliably measure functional capacity in women with lipedema.

  Recruiting Istanbul Physical Medicine Rehabilitation Training and Research Hospital · Istanbul, Bahcelievler · NCT07752017

• Turkish version of the Rapprich Lipedema Symptomatic Assessment Questionnaire

  This study tests whether the Turkish Rapprich Lipedema Symptomatic Assessment Questionnaire is reliable and valid for Turkish-speaking women with lipedema.

  Recruiting at 2 sites Marmara University · Istanbul, Kadıköy and 1 other locations · NCT07725146

• Personalized anti-inflammatory diet plus physical therapy for lipedema in women

  This study tests whether adding a personalized anti-inflammatory diet to standard physical therapy helps women with lipedema improve leg size, pain, and quality of life.

  Recruiting Balikesir University · Balıkesir · NCT07667270

• Endermologie-augmented physiotherapy after liposuction for lower-limb lipedema

  This study tests whether adding Endermologie to standard postoperative physiotherapy helps women recover better after liposuction for lower-limb lipedema.

  Recruiting Cairo University · Cairo, Nozha and 1 other locations · NCT07618065

• Venous findings in lipedema: how vein health relates to pain and function

  This study tests whether venous insufficiency seen on Doppler ultrasound is more common in people with lipedema and how it relates to pain, function, and quality of life.

  Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Uskudar · NCT07603076

• How Lipedema Affects Knee Osteoarthritis

  This study compares people with knee osteoarthritis who have lipedema to those with osteoarthritis but without lipedema to see if lipedema changes knee pain and structure.

  Recruiting Izmir Democracy University · Izmir, İzmir and 1 other locations · NCT07575555

• Metabolic markers linked to pain and central sensitization in women with lipedema

  This study will test whether metabolic measures like insulin resistance (HOMA-IR), triglyceride/HDL ratio, and HbA1c are linked to central sensitization and pain in women with lipedema.

  Recruiting Marmara University · Istanbul, Pendik · NCT07468097

• Medial longitudinal arch and foot function in women with lipedema

  This study tries to see if women with lipedema have flatter foot arches and worse foot function than age- and BMI-matched women with nonspecific foot pain.

  Recruiting Marmara University · Istanbul · NCT07294014

• Assessing the effectiveness of two types of compression garments for lipedema

  This study is testing whether circular or flat compression garments work better for helping people with lipedema manage swelling in their legs.

  Recruiting Instituto de Investigacion Sanitaria La Fe · Valencia, Valencia · NCT06964828

• Investigating central sensitization in patients with lipedema

  This study is trying to see if women with lipedema have different pain sensitivity compared to healthy individuals to help improve how the condition is diagnosed and treated.

  Recruiting Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey · Istanbul, Üsküdar · NCT06770634

• Biorepository for cardiovascular and metabolic disease research

  This study is collecting blood, urine, and stool samples from people with heart and metabolic diseases to help researchers better understand these conditions and improve care.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT05628948

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding blood vessel issues in lipedema

  This study is looking to better understand lipedema, a condition that causes unusual fat buildup in the legs, by using special MRI scans and simple tests to help improve how it's diagnosed and treated for people who often struggle with pain and emotional challenges.

  NIH research University of Virginia · Charlottesville, United States · NIH-11264614

Related topics

Quick answers

How many Lipedema clinical trials are recruiting right now?

18, as of November 12, 2026. 3 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in Turkey (Türkiye) (14 trials), Egypt (2 trials), United States (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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