Investigating central sensitization in patients with lipedema
Investigation of the Prevalence of Central Sensitization and Associated Factors in Patients With Lipedema
This study is trying to see if women with lipedema have different pain sensitivity compared to healthy individuals to help improve how the condition is diagnosed and treated.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Academic / other |
| Locations | 1 site (Istanbul, Üsküdar) |
| Trial ID | NCT06770634 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the presence of central sensitization and its associated factors in patients diagnosed with lipedema, a chronic condition affecting the lower extremities in women. The study will compare pain sensitivity and ultrasonographic findings between lipedema patients and healthy individuals. Participants will undergo various assessments, including pain-pressure threshold measurements and functional scales, to better understand the condition's impact. The findings may contribute to improved diagnosis and treatment strategies for lipedema.
Who should consider this trial
Good fit: Ideal candidates include women aged 18 to 65 diagnosed with lipedema or healthy individuals within the same age range without any metabolic issues.
Not a fit: Patients with concurrent conditions such as lymphedema, chronic venous insufficiency, or those outside the age range may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and management of lipedema, leading to better patient outcomes.
How similar studies have performed: While the investigation of central sensitization in lipedema is a relatively novel approach, similar studies in related conditions have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Lipedema; Diagnosis of lipedema Aged between 18 and 65 years Literate Willing to participate in the study 2. control group; Being completely healthy (no internal/metabolic issues such as diabetes, obesity, or hypothyroidism, and no diagnosis of lipedema) BMI ≤ 30 Aged between 18 and 65 years Literate Willing to participate in the study Exclusion Criteria: 1. Lipedema group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, or fibromyalgia Illiterate Not willing to participate in the study 2. Control group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, fibromyalgia, systemic rheumatic diseases, active cancer, infections, or pregnancy Illiterate Not willing to participate in the study
Where this trial is running
Istanbul, Üsküdar
- Sultan 2. Abdülhamid Han Eğitim ve Araştırma Hastanesi, İstanbul, Üsküdar 34000 — Istanbul, Üsküdar, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Zeynep Candan, MD
- Email: drzeynepcandan@gmail.com
- Phone: drzeynepcandan@gmail.com
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.