Turkish version of the Rapprich Lipedema Symptomatic Assessment Questionnaire
Official title: Turkish Validity and Reliability of the Rapprich Lipedema Symptomatic Assessment Questionnaire
Run by Marmara University · NCT07725146 · Data updated 2026-11-12
This study tests whether the Turkish Rapprich Lipedema Symptomatic Assessment Questionnaire is reliable and valid for Turkish-speaking women with lipedema.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | Women only |
| Enrollment | 180 (estimated) |
| Sponsor | Marmara University Academic / other |
| Locations | 2 sites (Istanbul, Kadıköy and 1 other locations) |
| Status | Recruiting |
| Started | July 17, 2026 |
| Main results expected | February 15, 2027 |
| Study ends | March 15, 2027 |
| Registry record updated | July 24, 2026 |
| Trial ID | NCT07725146 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult women (18–75) with clinician-diagnosed lipedema who consent to participate.
✕Probably not a fit
Patients with advanced lymphedema, pregnancy, BMI over 50, heart failure, or chronic kidney disease may not benefit from this instrument validation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will validate a Turkish translation of the Rapprich Lipedema Symptomatic Assessment Questionnaire. It will enroll 180 female participants with lipedema (stages I–III) from two Istanbul clinics. Participants will complete the Turkish questionnaire, the SF-36, and undergo physical measurements and a 6-minute walk test; results will be used to evaluate internal consistency, test-retest reliability, and construct validity through factor analyses. The study follows a cross-sectional design and uses standard statistical methods to determine the instrument's suitability for clinical and research use in Turkish-speaking patients.
Why it matters
Potential benefit: If successful, clinicians will have a validated Turkish tool to quantify lipedema symptom burden and track changes over time.
How similar studies have gone: Previous work with lipedema tools has shown promise; this study adapts a preexisting instrument for Turkish speakers and its success will depend on local validity and reliability results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female patients aged 18-75. * Diagnosed with lipedema by a clinician. * Willingness to participate and sign the informed consent form. Exclusion Criteria: * Positive Stemmer sign or presence of advanced-stage lymphedema. * Diagnosis of Heart Failure. * Chronic Kidney Disease. * Pregnancy. * BMI \> 50 kg/m².
Where it's running
-
Sultan 2. Abdülhamid Han Training and Research Hospital, Physical Medicine and Rehabilitation Clinic, Istanbul, Turkey.
Istanbul, Kadıköy, Turkey (Türkiye) Recruiting -
Marmara University Pendik Training and Research Hospital, Physical Medicine and Rehabilitation Department, Istanbul, Turkey.
Istanbul, Pendik, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Canan Şanal, Assoc. Prof. — Marmara University Faculty of Medicine
- Study coordinator: Canan Şanal, Assoc. Prof.
- Email: canansanal@hotmail.com
- Phone: +90 533 138 10 32
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.