Understanding blood vessel issues in lipedema
Visualizing vascular mechanisms of lipedema
This study is looking to better understand lipedema, a condition that causes unusual fat buildup in the legs, by using special MRI scans and simple tests to help improve how it's diagnosed and treated for people who often struggle with pain and emotional challenges.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-11264614 on NIH RePORTER |
What this research studies
This research aims to improve the understanding of lipedema, a condition characterized by abnormal fat accumulation in the lower body, by using advanced MRI techniques to visualize vascular and molecular dysfunction. The study will combine these imaging methods with portable clinical assessments of body fat and swelling to better characterize the disease. By identifying the unique features of lipedema, the research seeks to enhance diagnosis and treatment options for affected individuals, who often face significant pain and psychological distress due to misdiagnosis and inadequate care.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with lipedema, particularly those experiencing significant symptoms such as pain and swelling in the lower extremities.
Not a fit: Patients who do not have lipedema or those whose symptoms are solely related to obesity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for patients suffering from lipedema.
How similar studies have performed: Previous research has shown promising results in using advanced imaging techniques to differentiate lipedema from obesity, indicating that this approach has potential for success.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Crescenzi, Rachelle L — University of Virginia
- Study coordinator: Crescenzi, Rachelle L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.