Comparison of body composition in lipedema and obesity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cross-sectional observational study compares total and regional body composition in women with lipedema to BMI-matched women without lipedema using a TANITA segmental bioelectrical impedance device. It measures fat mass, fat percentage, fat-free mass, and muscle mass in the arms, legs, and trunk, and computes regional distribution indices. The study also explores how these measurements relate to disease type and stage, duration, pain, and lower-extremity function, using validated patient-reported outcomes. Anthropometrics and lipedema-related clinical features are recorded, and findings aim to identify objective body composition indicators to complement clinical assessment. Results may inform future validation studies and contribute to a more comprehensive approach to evaluating lipedema.”,

Why it matters

Who can join: the full rules

Inclusion Criteria:

1\. Inclusion Criteria (Lipedema Group)

1. Being female.
2. Being between 18-65 years of age.
3. Having received a diagnosis of lipedema based on clinical evaluation.
4. Being willing to participate in the study and signing the written informed consent form.

2\. Inclusion Criteria (BMI-Matched Obese Group)

1. Being female.
2. Being between 18-65 years of age.
3. Not meeting the diagnostic criteria for lipedema on clinical evaluation.
4. Showing similar characteristics to the lipedema group in terms of age and BMI.
5. Being willing to participate in the study and signing the written informed consent form.

Exclusion Criteria:

1. Being pregnant or breastfeeding.
2. Having a diagnosis of primary or secondary lymphedema.
3. Having clinically advanced-stage chronic venous insufficiency, an active venous ulcer, or a history of acute deep vein thrombosis.
4. Having a history of surgery or serious trauma within the last 6 months.
5. Having an active infection, cellulitis, or open wound.
6. Presence of edema due to congestive heart failure, advanced renal failure, or decompensated liver disease.
7. Having a diagnosis of active malignancy.
8. Having a neurological, rheumatological, or serious musculoskeletal disease that could affect the assessment.
9. Being unable to comply with study procedures or not providing informed consent.

Where it's running

• Department of Physical Medicine and Rehabilitation, Health Sciences University Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Uskudar
  Istanbul, Uskudar, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Feyza Nur Yücel, Assoc. Prof. — Saglik Bilimleri Universitesi
• Study coordinator: Feyza Nur Yücel, Assoc. Prof.
• Email: dr.fny28@gmail.com
• Phone: 2165422000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.