Condition
Lidocaine clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Lidocaine clinical trials that are recruiting, at sites in 3 countries (most in Egypt (5), France (1), Canada (1)). By phase: Phase 3 (1), Phase 4 (1). The most active sponsors are Tanta University (2), Cairo University (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 3Countries
Newest Lidocaine clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Dexmedetomidine vs magnesium with lidocaine for eye block during DCR surgery | — | Cairo | Recruiting | Jun 30, 2026 |
| Minimal Effective Volume for double-injection costoclavicular block | Phase 4 | Montreal, Quebec | Recruiting | Jan 29, 2026 |
| IV lidocaine versus IV dexmedetomidine for pain control during sleeve gastrectomy | — | Alexandria | Recruiting | Jan 8, 2026 |
| Lidocaine versus dexmedetomidine during abdominal surgery to protect brain oxygen and reduce delirium in older adults | — | Tanta, El-Gharbia | Recruiting | Aug 7, 2025 |
| Sevoflurane (with or without IV lidocaine) versus propofol for intracranial pressure and brain oxygen during laparoscopic hysterectomy | — | Tanta, El-Gharbia | Recruiting | Jul 14, 2025 |
| Comparing dexmedetomidine and lidocaine for pain management after mastectomy | — | Cairo | Recruiting | Apr 4, 2025 |
| Serratus plane block to reduce pain during pleural drainage in the ICU. | Phase 3 | Amiens | Recruiting | Jun 13, 2019 |
All recruiting trials (7)
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Dexmedetomidine vs magnesium with lidocaine for eye block during DCR surgery
This trial tests whether adding dexmedetomidine or magnesium sulfate to lidocaine for a preemptive peribulbar block can better manage blood pressure and heart rate in adults undergoing DCR surgery under general anesthesia.
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Minimal Effective Volume for double-injection costoclavicular block
This study tests the smallest amount of lidocaine that still provides a successful double-injection costoclavicular nerve block in adults having upper-extremity surgery.
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IV lidocaine versus IV dexmedetomidine for pain control during sleeve gastrectomy
It tests whether an IV infusion of lidocaine or dexmedetomidine given during laparoscopic sleeve gastrectomy helps reduce early postoperative pain and the need for opioid pain medicines in adults aged 20–50 with BMI 35–50.
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Lidocaine versus dexmedetomidine during abdominal surgery to protect brain oxygen and reduce delirium in older adults
This trial tests whether giving lidocaine or dexmedetomidine during major abdominal surgery helps keep brain oxygen levels stable and reduces postoperative delirium in people aged 65 and older.
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Sevoflurane (with or without IV lidocaine) versus propofol for intracranial pressure and brain oxygen during laparoscopic hysterectomy
This study will test whether sevoflurane (with or without an IV lidocaine infusion) or propofol anesthesia better controls intracranial pressure and cerebral oxygenation in adult women having laparoscopic hysterectomy.
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Comparing dexmedetomidine and lidocaine for pain management after mastectomy
This study is testing whether dexmedetomidine or lidocaine works better for managing pain after mastectomy surgery in adults aged 18 to 75.
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Serratus plane block to reduce pain during pleural drainage in the ICU.
This study will test whether a serratus plane nerve block with lidocaine reduces pain for awake adults in the ICU who need pleural drainage.
Related topics
Quick answers
How many Lidocaine clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in Egypt (5 trials), France (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.