Comparing dexmedetomidine and lidocaine for pain management after mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of dexmedetomidine and lidocaine infusions as adjuvants to general anesthesia in managing chronic pain following mastectomy. Chronic pain is a significant issue for patients undergoing breast cancer surgery, and this research aims to determine which infusion provides better pain relief. The study involves patients aged 18 to 75 who are scheduled for mastectomy with axillary dissection and evaluates the outcomes of both medications in a controlled setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age from 18 to 75 years.
* American Society of Anesthesiologists (ASA) physical status II.
* Scheduled for mastectomy with axillary dissection (either modified radical mastectomy with or without latissimus dorsi flap or conservative breast surgery) due to breast cancer.

Exclusion Criteria:

* Patient refusal.
* Known allergy to any of the study drugs.
* Those with hepatic or renal insufficiency.
* Patients who are running regularly on B blockers.
* α2 adrenergic agonists and sedatives.
* Psychoactive medications.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed E Abdel Fattah, MD
• Email: mohamed-elsaid@cu.edu.eg
• Phone: 00201284475792

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.