Serratus plane block to reduce pain during pleural drainage in the ICU.
Official title: Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.
Run by Centre Hospitalier Universitaire, Amiens · NCT03984656 · Data updated 2026-11-12
This study will test whether a serratus plane nerve block with lidocaine reduces pain for awake adults in the ICU who need pleural drainage.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | June 4, 2019 |
| Main results expected | September 6, 2026 |
| Study ends | September 6, 2026 |
| Registry record updated | May 13, 2026 |
| Trial ID | NCT03984656 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are conscious, non‑intubated adults in the ICU who require pleural drainage, can give informed consent, and have no contraindication to local anesthetics or coagulation disorders.
✕Probably not a fit
Patients who are intubated or sedated, pregnant or breastfeeding, under legal guardianship, have coagulation disorders, or have contraindications to lidocaine/ropivacaine may not benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Pleural drainage under local anesthesia is often painful for conscious ICU patients, and better pain control may help early rehabilitation and shorten ICU stay. This Phase 3 interventional study will compare a serratus plane block using lidocaine with standard local anesthesia in non‑intubated ICU patients undergoing pleural drainage. Investigators will record pain scores during and after the procedure, opioid consumption, patient satisfaction, and any block‑related complications. Participants are adult, conscious ICU patients without contraindications to local anesthetics or coagulopathy and able to give informed consent, treated at CHU Amiens.
Why it matters
Potential benefit: If effective, the serratus plane block could provide better pain relief during pleural drainage, reduce opioid use, and improve recovery for ICU patients.
How similar studies have gone: Serratus plane block has reduced pain and opioid use after thoracic and breast surgery in prior studies, but it has not been tested specifically for pleural drainage in ICU patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients over 18 years old. * non-intubated patient with spontaneous ventilation * free and informed consent of the patient, * affiliated to a social security scheme * hospitalized in ICU unit including surgical ICU, cardiothoracic and respiratory ICU or cardiothoracic and respiratory continuous care unit. * requiring pleural drainage gas or fluid * conscious patient, not sedated. Exclusion Criteria: * patient under the age of 18 years old. * patient refusal * under curatorship or deprivation of liberty * pregnant, parturient or breastfeeding woman * contraindication to Lidocaine or Ropivacaine * coagulation disorders
Where it's running
-
CHU Amiens
Amiens, France Recruiting
Study contacts
- Principal investigator: Louise Badoux, MD — CHU amiens
- Study coordinator: Louise Badoux, MD
- Email: badoux.louise@chu-amiens.fr
- Phone: (33)322087877
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.