Dexmedetomidine vs magnesium with lidocaine for eye block during DCR surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two adjuvants—dexmedetomidine and magnesium sulfate—mixed with lidocaine for a preemptive peribulbar block in adults undergoing elective dacryocystorhinostomy under general anesthesia. The goal is to observe how these adjuvants influence intraoperative hemodynamics. Participants are adults (ASA I–II) undergoing DCR, with exclusions including coagulopathy, infections at the injection site, uncontrolled systemic disease, and uncooperative behavior. The trial assesses whether one adjuvant provides more stable hemodynamics or better analgesia compared to the other or lidocaine alone. Lead institution is Cairo University.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I or II.
* Undergoing elective Dacryocystorhinostomy (DCR) surgery under general anesthesia.

Exclusion Criteria:

* Patients have local infection.
* Allergic reaction or complications of the local anaesthesia (LA).
* Coagulopathy defined as international normalized ratio (INR) \> 1.5, platelet count \< 100,000/mm³, or ongoing anticoagulant therapy not adequately discontinued.
* Uncontrolled systemic disease, defined as poorly controlled hypertension \[systolic blood pressure (SBP) \> 160 mmHg\], uncontrolled diabetes mellitus (HbA1c \> 8.5%), unstable ischemic heart disease, or decompensated hepatic or renal disease.
* Uncooperative patients.

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Hebatullah S Abdelhamid, MD
• Email: drhebasalah593@gmail.com
• Phone: 00201044512277

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.