Condition

Juvenile Idiopathic Arthritis clinical trials and research

• 17Clinical trials
• 10NIH research projects
• 1New in 30 days
• 32Countries

Newest Juvenile Idiopathic Arthritis clinical trials

All recruiting trials (17)

• Using infrared cameras to help detect juvenile arthritis in kids

  This study tests whether infrared thermography can help identify joint inflammation in children with juvenile idiopathic arthritis compared with standard tests.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07914179

• Oral health, saliva bacteria, and disease activity in children with JIA

  This study checks if how active juvenile idiopathic arthritis is relates to oral health in children who already receive rheumatology care.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Pudongxinqu · NCT07799831

• Olokizumab treatment for children with polyarticular juvenile idiopathic arthritis

  This test gives weight-based doses of olokizumab every 4 weeks to see if it helps control polyarticular juvenile idiopathic arthritis and is safe for children aged 2–17.

  Recruiting at 14 sites Phase 2 R-Pharm · Kazan' and 13 other locations · NCT07517575

• Post-marketing surveillance of Cosentyx (secukinumab) for hidradenitis suppurativa, pediatric plaque psoriasis, and juvenile idiopathic arthritis in Korea

  This study will see how Cosentyx (secukinumab) works and is tolerated in people in Korea with moderate-to-severe hidradenitis suppurativa, pediatric plaque psoriasis, or juvenile idiopathic arthritis who are being treated in routine care.

  Recruiting Novartis · Seoul, Seoul · NCT07243782

• Understanding pain in juvenile idiopathic arthritis

  This project will test whether temperature and pressure pain tests, questionnaires, and blood or saliva samples can help explain pain in kids and teens (ages 9–17) with juvenile idiopathic arthritis.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07217782

• Follow-up care for new cases of polyarthritis in children and young adults

  This program will try standardized medical follow-up for children and young adults (≤50) with new-onset JIA, RA, psoriatic/seronegative/undifferentiated arthritis, SLE, or diffuse systemic sclerosis who are treatment-naïve or treated ≤3 months to see if more patients reach disease control or remission.

  Recruiting Université Catholique de Louvain · Brussels · NCT07000916

• Assessing walking function in children with juvenile idiopathic arthritis

  This study is testing a walking assessment tool to see how well it can identify walking problems in children with juvenile idiopathic arthritis.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Turkey · NCT06870045

• Optimizing treatment strategies for children with Juvenile Idiopathic Arthritis in remission

  This study is testing three different ways to adjust treatment for children with Juvenile Idiopathic Arthritis who are doing well to see which method keeps them healthy the longest.

  Recruiting at 7 sites Phase 4 Oslo University Hospital · Bergen and 6 other locations · NCT06653634

• Personalized medicine network for childhood arthritis and rheumatic disease

  This study is trying to find out how to better treat children with juvenile idiopathic arthritis by collecting information and samples to help doctors choose the right medications at the right time.

  Recruiting at 19 sites The Hospital for Sick Children · Calgary, Alberta and 18 other locations · NCT06560606

• Mediterranean-style diet for children with juvenile arthritis

  This study will try a Mediterranean-style diet in children aged 8–18 with juvenile idiopathic arthritis to see if it improves arthritis symptoms and changes the gut microbiome.

  Recruiting at 4 sites The Hospital for Sick Children · Winnipeg, Manitoba and 6 other locations · NCT06474546

• Mindfulness program for children with Juvenile Idiopathic Arthritis

  This study is testing a mindfulness program for kids with Juvenile Idiopathic Arthritis and their caregivers to see if it helps them cope better and feel healthier.

  Recruiting at 3 sites London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Hamilton, Ontario and 2 other locations · NCT06376149

• Evaluating Upadacitinib and Tocilizumab for Treating Systemic Juvenile Idiopathic Arthritis in Children

  This study is testing whether a new drug called upadacitinib is safe and effective for children and teens with systemic juvenile idiopathic arthritis compared to an existing treatment called tocilizumab.

  Recruiting at 40 sites Phase 3 AbbVie · Phoenix, Arizona and 44 other locations · NCT05609630

• Personalized treatment discussions for children with juvenile arthritis

  This study is trying to see if having personalized treatment discussions between doctors and families can help children who are newly diagnosed with juvenile arthritis make better decisions about their care.

  Recruiting University of British Columbia · Vancouver, British Columbia · NCT05310799

• Developing a way to measure treatment effects in children with rheumatologic conditions

  This study is trying to find a better way to measure how well treatments work for kids with certain rheumatologic conditions like Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, and Fibromyalgia.

  Recruiting Children's National Research Institute · Washington D.C., District of Columbia · NCT04833465

• Assessing health and exercise responses in children with chronic diseases

  This study is testing how chronic diseases and their treatments affect physical fitness in children and teens to find ways to improve their health and quality of life through exercise.

  Recruiting University Hospital, Clermont-Ferrand · Clermont-Ferrand · NCT03913962

• Evaluating baricitinib for treating juvenile idiopathic arthritis in children

  This study tests if continuing treatment with baricitinib helps children with juvenile idiopathic arthritis feel better and stay safe.

  Recruiting at 46 sites Phase 3 Eli Lilly and Company · Rosario and 76 other locations · NCT03773965

• Finding the right dose of sarilumab for children with systemic juvenile idiopathic arthritis

  This study is testing the right dose of sarilumab to see how well it works and how safe it is for children and teens with systemic juvenile idiopathic arthritis.

  Recruiting at 33 sites Phase 2 Sanofi · San Miguel de Tucumán, Tucumán Province and 39 other locations · NCT02991469

NIH-funded research (10)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Deciphering What Drives Juvenile Idiopathic Arthritis in African American Children

  This project looks at why African American children with juvenile idiopathic arthritis have more joint damage, using clinical data and genetic information to find factors that may explain the differences.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11442239

• Understanding how T cells make IFN-γ and IL-17 in kids with juvenile arthritis

  A doctor-scientist at Vanderbilt is studying why certain immune cells in children with juvenile idiopathic arthritis produce inflammatory signals, with the goal of improving diagnosis and treatment.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11392245

• Lung disease linked to systemic juvenile idiopathic arthritis in children

  This project looks at how ongoing immune activation and some arthritis medicines may cause lung inflammation and breathing problems in children with systemic juvenile idiopathic arthritis (SJIA).

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11326213

• Linking JIA Registry with Claims Data to Improve Understanding of Juvenile Arthritis

  A study will connect the CARRA JIA patient registry with a large national claims database to see how well registry data match real-world care and outcomes for children with juvenile idiopathic arthritis.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-11295916

• Investigating the role of viruses and gut bacteria in arthritis flares in children

  This study is looking at how certain viruses and bacteria in the gut might affect flare-ups of juvenile idiopathic arthritis in kids, hoping to find clues that could help manage these painful episodes better.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11056288

• Understanding lung disease in children with systemic juvenile idiopathic arthritis

  This study is looking at how a serious lung problem in some kids with systemic juvenile idiopathic arthritis happens, and it aims to find new ways to help treat or prevent this issue by understanding how a certain part of their immune system works.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-11042812

• Understanding how immune cells produce inflammatory signals in children with arthritis

  This study is looking at how certain immune cells in children with juvenile idiopathic arthritis produce substances that cause inflammation, and it hopes to find genetic clues that could help improve how we diagnose and treat this condition.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10903950

• Predicting eye inflammation in children with juvenile arthritis

  This study is looking to help kids with juvenile idiopathic arthritis by finding better ways to spot and treat uveitis, an eye condition they might get, by checking their tears and genes to see who might be at risk.

  NIH research Cincinnati Childrens Hosp Med Ctr · Cincinnati, United States · NIH-10661602

• Stopping adalimumab treatment for children with arthritis-related eye inflammation

  This study is looking at what happens when kids with juvenile idiopathic arthritis stop taking adalimumab, a medicine for eye inflammation, to see if they can safely go off it without their symptoms coming back.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10626013

• The impact of antibiotics on juvenile idiopathic arthritis and treatment response

  This study is looking at how taking antibiotics might affect kids with juvenile idiopathic arthritis (JIA) and how well their treatments work, with a special focus on the good bacteria in their gut, to help find better ways to treat JIA in children.

  NIH research Rutgers Biomedical and Health Sciences · Newark, UNITED STATES · NIH-10442518

Related topics

Quick answers

How many Juvenile Idiopathic Arthritis clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 32 countries. The most sites are in Canada (5 trials), France (4 trials), United States (3 trials), Turkey (Türkiye) (3 trials), Argentina (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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