Personalized treatment discussions for children with juvenile arthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The PERSON-JIA Trial is a cluster-randomized trial that evaluates the effectiveness of Shared Decision Making (SDM) between physicians and families for children newly diagnosed with Juvenile Idiopathic Arthritis (JIA). The intervention involves structured discussions guided by personalized outcome reports generated from prediction algorithms, which provide insights into expected disease severity and treatment effectiveness. By utilizing data from previous cohorts, the trial aims to enhance treatment tailoring and disease control through informed decision-making. The study also incorporates a registry for real-time data entry to support ongoing patient management.

Why it matters

Who can join: the full rules

Physicians (Inclusion):

1. Licensed to practice pediatric rheumatology in Canada;
2. Providing care for children with JIA at least once a month;
3. Consent to be randomized and to implement the SDM intervention for the duration of the trial, if randomized to the intervention arm;
4. Commit to propose enrollment in the Registry to all their newly diagnosed patients with JIA during the trial.

Physicians (Exclusion):

1. Fellows-in-training;
2. Physicians planning to retire within 2 years.

Patient (Inclusion):

1. Consent to include their information in the CAPRI JIA Registry;
2. Consent to the PERSON-JIA trial and answering additional questionnaires to assess decision making;
3. Allow recording of their medical encounter (if selected at random);
4. JIA fulfilling International League of Associations for Rheumatology (ILAR) criteria;
5. Newly diagnosed (within the last month);
6. Diagnosed by a pediatric rheumatologist participating in the PERSON-JIA study;
7. Not yet receiving treatment, or received only Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) or joint injections;

Patient (Exclusion):

1. Systemic arthritis category of JIA (it requires a different treatment approach);
2. Family is unable to complete study forms in English or French;
3. Patients who have already started systemic corticosteroid or any Disease Modifying Anti-Rheumatic Drug (DMARD).

Where it's running

• BC Children's Hospital
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Principal investigator: Lori B Tucker, MD — University of British Columbia Department of Pediatrics
• Study coordinator: Jaime Guzman
• Email: jguzman@cw.bc.ca
• Phone: 604 875 2000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using infrared cameras to help detect juvenile arthritis in kids

  This study tests whether infrared thermography can help identify joint inflammation in children with juvenile idiopathic arthritis compared with standard tests.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07914179

• Oral health, saliva bacteria, and disease activity in children with JIA

  This study checks if how active juvenile idiopathic arthritis is relates to oral health in children who already receive rheumatology care.

  Recruiting Shanghai Jiao Tong University School of Medicine · Shanghai, Pudongxinqu · NCT07799831

• Olokizumab treatment for children with polyarticular juvenile idiopathic arthritis

  This test gives weight-based doses of olokizumab every 4 weeks to see if it helps control polyarticular juvenile idiopathic arthritis and is safe for children aged 2–17.

  Recruiting at 14 sites Phase 2 R-Pharm · Kazan' and 13 other locations · NCT07517575

• Post-marketing surveillance of Cosentyx (secukinumab) for hidradenitis suppurativa, pediatric plaque psoriasis, and juvenile idiopathic arthritis in Korea

  This study will see how Cosentyx (secukinumab) works and is tolerated in people in Korea with moderate-to-severe hidradenitis suppurativa, pediatric plaque psoriasis, or juvenile idiopathic arthritis who are being treated in routine care.

  Recruiting Novartis · Seoul, Seoul · NCT07243782

• Understanding pain in juvenile idiopathic arthritis

  This project will test whether temperature and pressure pain tests, questionnaires, and blood or saliva samples can help explain pain in kids and teens (ages 9–17) with juvenile idiopathic arthritis.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT07217782

• Follow-up care for new cases of polyarthritis in children and young adults

  This program will try standardized medical follow-up for children and young adults (≤50) with new-onset JIA, RA, psoriatic/seronegative/undifferentiated arthritis, SLE, or diffuse systemic sclerosis who are treatment-naïve or treated ≤3 months to see if more patients reach disease control or remission.

  Recruiting Université Catholique de Louvain · Brussels · NCT07000916

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.