Comparing two imaging techniques for detecting arterial obstructions in stroke patients
Accuracy of Transcranial Colour Coded Duplex Compared With CT Angiography in Diagnosing Arterial Obstructions in Acute Ischemic Strokes
This study is testing whether a new imaging method called TCCD is better than CT angiography for finding blocked arteries in stroke patients, especially in the Egyptian population.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06920303 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the accuracy of transcranial colour coded duplex (TCCD) in comparison to CT angiography for detecting arterial obstructions in patients who have experienced acute ischemic strokes or transient ischemic attacks. The study focuses on understanding the prevalence of intracranial stenosis and its implications in different ethnic groups, particularly in the Egyptian population, where data is scarce. By assessing the effectiveness of TCCD, the study seeks to provide insights into a potentially less invasive imaging method for stroke diagnosis. The findings could enhance the understanding of stroke mechanisms and improve diagnostic approaches in clinical settings.
Who should consider this trial
Good fit: Ideal candidates for this study are patients presenting with acute ischemic strokes or transient ischemic attacks.
Not a fit: Patients with a history of cardiac arrhythmia, autoimmune diseases, or those with significant neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic accuracy for ischemic strokes, potentially allowing for better-targeted treatments.
How similar studies have performed: While there is extensive data on carotid atherosclerosis in various populations, this study's focus on the Egyptian ethnic group represents a novel approach that has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients who have acute ischemic strokes or transient ischemic attacks . Exclusion Criteria: 1. Patients with history of cardiac arrhythmia or discovered recently or known rheumatic heart disease. 2. Patients with history of autoimmune diseases. 3. Patients with space occupying lesion or hemorrhage in Ct brain. 4. Pregnant female. 5. Patients who refuse to participate in the study. 6. Patients who have history of allergy or developed acute kidney injury during previous dye injection. 7. Patients who have chronic kidney disease. 8. Premorbid neurological disorder (myopathy, multiple sclerosis) on neurological examination or previous investigations. 9. Inability to achieve safe vascular access. 10. Patients with insufficient temporal acoustic window.
Where this trial is running
Sohag
- Sohag university hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Hassan H Accuracy of Transcranial Colour Coded duplex Compared With CT, resident
- Email: hassan.hamdy@med.sohag.edu.eg
- Phone: +2001060583440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.