Effects of iron deficiency anemia on brain development in late childhood

Neurocognitive Effects of Late-Childhood Iron Deficiency Anemia

NIH-funded research Washington University · NIH-10881010

This study is looking at how iron deficiency anemia in girls aged 12 to 21 affects their brain development and thinking skills, and it will involve some tests and brain scans to see how their brains are working during this important time in their lives.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10881010 on NIH RePORTER

What this research studies

This research investigates how iron deficiency anemia (IDA) in late childhood affects brain development and cognitive function in young females. It focuses on understanding the short and long-term impacts of IDA, particularly how it causes cerebral metabolic stress that may lead to changes in cognitive abilities. Participants aged 12 to 21 with IDA will undergo cognitive evaluations and brain MRI scans to assess their brain's metabolism and connectivity. The study aims to provide insights into the neurocognitive consequences of IDA during a critical period of brain development.

Who could benefit from this research

Good fit: Ideal candidates for this research are young females aged 12 to 21 who are diagnosed with iron deficiency anemia.

Not a fit: Patients outside the age range of 12 to 21 or those without iron deficiency anemia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved screening and treatment strategies for iron deficiency anemia, ultimately enhancing cognitive outcomes for affected individuals.

How similar studies have performed: Previous research has shown significant neurocognitive impacts of early childhood iron deficiency anemia, suggesting that this investigation into late-childhood IDA is both relevant and necessary.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.