Condition

Immune-related Adverse Event clinical trials and research

• 12Clinical trials
• 3NIH research projects
• 6Countries

Newest Immune-related Adverse Event clinical trials

All recruiting trials (12)

• Mycophenolate mofetil with prednisone for immune-related hepatitis from cancer therapy

  This study tests whether starting mycophenolate mofetil plus prednisone can help liver inflammation caused by immune checkpoint inhibitors in adults with moderate to severe immune-related hepatitis.

  Recruiting Phase 2 Fox Chase Cancer Center · Philadelphia, Pennsylvania · NCT07663422

• Thymosin Alpha-1 plus PD-1 therapy in older adults with advanced melanoma

  This trial tests whether adding Thymosin Alpha-1 to a PD-1 antibody helps people age 60 and up with advanced melanoma.

  Recruiting at 2 sites Phase 2 Sun Yat-sen University · Guangzhou, Guangdong and 1 other locations · NCT07644897

• Inhaled budesonide to prevent recurrent checkpoint inhibitor–related pneumonitis

  This study tests whether adding inhaled budesonide to usual care can prevent recurrence of pneumonitis in adults who developed grade 2 or higher lung inflammation from checkpoint inhibitor immunotherapy.

  Recruiting Phase 2 AHS Cancer Control Alberta · Calgary, Alberta · NCT06860542

• Investigating serum ferritin as a biomarker for immune-related adverse events

  This study is testing if a blood marker called serum ferritin can help doctors identify and predict immune-related side effects in patients with cancer receiving different types of treatment.

  Recruiting Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT06702566

• Exploring PD-1 therapy duration for rectal cancer treatment

  This study is testing how long PD-1 therapy should be given to people with stage II-III rectal cancer to see if it helps them have the best chance of a complete response before surgery.

  Recruiting Xijing Hospital · Xi'an, Shaanxi · NCT06613165

• Vedolizumab to prevent ICI-related diarrhea or colitis in cancer patients

  This study tests whether vedolizumab can prevent immune checkpoint inhibitor–related diarrhea or colitis in adults with unresectable or metastatic melanoma, lung, or kidney cancer starting immunotherapy.

  Recruiting Phase 2/3 AHS Cancer Control Alberta · Calgary, Alberta and 1 other locations · NCT06337695

• Evaluating dostarlimab as a non-surgical treatment for early-stage endometrial cancer

  This study is testing if a new immunotherapy drug called dostarlimab can be a safe and effective non-surgical treatment for women with early-stage endometrial cancer who want to keep their fertility or can't have surgery.

  Recruiting at 2 sites Phase 2 Queensland Centre for Gynaecological Cancer · Sydney, New South Wales and 2 other locations · NCT06278857

• Using Adalimumab to treat early inflammatory arthritis caused by immune checkpoint inhibitors

  This study is testing if adalimumab can help people with early inflammatory arthritis caused by cancer treatments to feel better and rely less on steroids.

  Recruiting Phase 2 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06037811

• Dietary fiber intervention to reduce immunotherapy side effects

  This study is testing if eating more fiber from a variety of plants can help people with solid tumors have fewer side effects from their immunotherapy treatment.

  Recruiting Universitair Ziekenhuis Brussel · Jette · NCT05832606

• Identifying biomarkers for immune-related side effects in cancer patients receiving immunotherapy

  This study is trying to find out if certain blood markers can help predict which cancer patients receiving immunotherapy are more likely to experience serious side effects.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens, Picardie · NCT05813418

• Assessment of cardiovascular issues in cancer patients on immune checkpoint inhibitors

  This study is trying to see if cancer patients treated with immune checkpoint inhibitors have heart problems and how those issues affect their health.

  Recruiting Institut Mutualiste Montsouris · Paris · NCT05799898

• Mesalamine to prevent colitis from ipilimumab plus nivolumab

  This trial will try giving mesalamine to adults with advanced melanoma who are starting ipilimumab plus nivolumab to see if it lowers the chance and severity of immune-related diarrhea and colitis.

  Recruiting Phase 2 AHS Cancer Control Alberta · Edmonton, Alberta · NCT05663775

NIH-funded research (3)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Informatics tools to better detect immune-related side effects in cancer patients

  A new informatics approach using smart language models will help doctors identify and track immune-related side effects from cancer immunotherapy in electronic health records, aiming to improve patient care.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11391040

• AI to detect immune-related side effects after cancer immunotherapy

  This project uses AI language models to find and flag immune-related side effects in medical records of people treated with immune checkpoint inhibitor cancer therapies.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11174438

• Improving detection of immune-related side effects in cancer patients

  This study is looking to make it easier to spot side effects that can happen to cancer patients using new immune treatments, so if you join, your health records will help us learn how to better track and understand these issues for better care.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10979489

Related topics

Quick answers

How many Immune-related Adverse Event clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in Canada (4 trials), China (3 trials), France (2 trials), United States (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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