Evaluating early inflammatory polyarthritis for better treatment outcomes
Official title: Early Prediction of Patient-related and Radiological Outcomes in Patients With Recent-onset Inflammatory Polyarthritis (EPA) Using Established and Novel Independent Predictors
Run by Université de Sherbrooke · NCT00512239 · Data updated 2026-11-12
This study is trying to find out if certain blood markers can help doctors identify early on which patients with inflammatory polyarthritis, especially rheumatoid arthritis, might need stronger treatment to avoid severe disease.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Université de Sherbrooke Academic / other |
| Locations | 1 site (Sherbrooke, Quebec) |
| Status | Recruiting |
| Started | July 1998 |
| Main results expected | December 2030 |
| Study ends | December 2035 |
| Registry record updated | March 25, 2025 |
| Trial ID | NCT00512239 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with early rheumatoid arthritis or early inflammatory arthritis.
✕Probably not a fit
Patients with infectious arthritis or microcrystalline arthritis will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the prognostic markers in patients with early inflammatory polyarthritis, particularly focusing on rheumatoid arthritis. It seeks to identify which patients are likely to experience persistent and severe disease based on the presence of specific autoantibodies, such as anti-Sa and anti-CCP antibodies. By evaluating these markers over a period of 60 months, the study intends to improve treatment strategies by determining who should receive aggressive therapy early in their disease course. The study is conducted at the Centre hospitalier universitaire de Sherbrooke in Quebec, Canada.
Why it matters
Potential benefit: If successful, this study could lead to more targeted and effective treatment strategies for patients with early inflammatory arthritis, potentially reducing long-term disability.
How similar studies have gone: Other studies have shown promise in using biomarkers for risk stratification in rheumatoid arthritis, suggesting that this approach may yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Early Rheumatoid arthritis * Early Inflammatory Arthritis Exclusion Criteria: * Refusal or inability to consent * Infectious arthritis * Microcrystalline arthritis
Where it's running
-
Centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec, Canada Recruiting
Study contacts
- Principal investigator: Gilles Boire, MD, MSc — Centre de recherche du Centre hospitalier universitaire de Sherbrooke
- Study coordinator: Gilles Boire, MD, MSc
- Email: Gilles.Boire@USherbrooke.ca
- Phone: (819) 564-5261
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.