Antenatal DMARD Use and Mother-Child Health in Women with Chronic Inflammatory Arthritis
Official title: Use of Antenatal Disease Modifying Antirheumatic Drugs and Maternal-child Health Among Women with Chronic Inflammatory Arthritis
Funded at Yale University · NIH-11452559 · Data updated 2026-11-12
This project aims to understand how continuing pregnancy-safe arthritis medicines during pregnancy affects health outcomes for mothers with chronic inflammatory arthritis and their babies.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $160,024 |
| NIH project number | 1K08AR086996-01A1 |
| Project ID | NIH-11452559 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women with chronic inflammatory arthritis who are pregnant or planning pregnancy and are considering DMARD therapy.
✕Less likely to help
If a patient does not have CIA or is not pregnant, this study is not directly applicable.
What this research studies
Pregnant women with chronic inflammatory arthritis often stop medicines due to safety concerns, which may affect both mother and child. This research will use real-world data to compare outcomes when DMARDs are continued at different pregnancy stages versus when they are not taken. The study is led by a rheumatologist with training in epidemiology and will apply advanced perinatal methods to analyze long-term health effects on children and maternal health. The goal is to provide clear evidence to guide safer, more effective treatment during pregnancy for women with CIA.
Why it matters
Potential benefit: If successful, the findings could help clinicians and patients make better decisions about during-pregnancy treatment to improve health for both mothers and their children.
How similar studies have gone: Previous work in perinatal pharmacoepidemiology suggests real-world data can reveal meaningful maternal-child health patterns, but this specific DMARD-pregnancy question is still emerging.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Chock, Eugenia Yupei — Yale University
- Study coordinator: Chock, Eugenia Yupei
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.