Condition

High Blood Pressure clinical trials and research

• 17Clinical trials
• 9NIH research projects
• 8Countries

Newest High Blood Pressure clinical trials

All recruiting trials (17)

• See if stopping alcohol can lower blood pressure and heart risk in adults who drink and have hypertension

  This study tests whether abstaining from alcohol for 8 weeks can improve blood pressure and heart-health markers in adults who regularly drink and have high blood pressure.

  Recruiting The University of Texas at Arlington · Arlington, Texas · NCT07783061

• IsoLG scavenger 2-HOBA for salt sensitivity of blood pressure

  This study tests whether the IsoLG scavenger 2-HOBA can reduce salt sensitivity and immune activation in adults with salt-sensitive hypertension.

  Recruiting Phase 2 Vanderbilt University Medical Center · Nashville, Tennessee · NCT07602166

• Postpartum Cardiovascular Care After Pregnancy

  This study tests whether a postpartum education program can improve blood pressure and early heart‑health markers in women in their third trimester to six months after giving birth in Accra, Ghana.

  Recruiting University of North Carolina, Greensboro · Accra · NCT07420465

• BPCARE: Community health worker support to improve blood pressure and medication use

  This trial will test whether community health workers can help adult refugees with high blood pressure take their medicines and keep their blood pressure under control compared with enhanced usual care.

  Recruiting University of California, San Diego · San Diego, California and 1 other locations · NCT07398391

• Electrical stimulation plus isometric exercise to improve blood flow in resistant high blood pressure

  This will try whether adding upper‑thoracic electrical stimulation (TENS) and isometric exercise to usual blood pressure medications can lower blood pressure and improve peripheral blood flow in men and women aged 50–60 with resistant hypertension.

  Recruiting Cairo University · Port Said, Port Said Governorate · NCT07383220

• Corin gene double variant (Thr555Ile and Glu568Pro) and high blood pressure risk in Afro‑Caribbean adults

  This study will test whether two corin gene variants (Thr555Ile and Glu568Pro) are linked to high blood pressure in Afro‑Caribbean adults in Guadeloupe.

  Recruiting Centre Hospitalier Universitaire de la Guadeloupe · Petit-Bourg and 1 other locations · NCT07330804

• Fast control of resistant high blood pressure in Brazil's public health system

  This will see if a single-pill triple combination (perindopril, indapamide, amlodipine) controls blood pressure better than usual separate-pill regimens in adults with apparent resistant hypertension.

  Recruiting Instituto Dante Pazzanese de Cardiologia · São Paulo, São Paulo · NCT07259733

• Improving hypertension care in Ghana and Baltimore

  This program tests whether a package of patient-, provider-, and health-system interventions can improve blood pressure control for adults ages 18–70 with hypertension who receive care at participating clinics and own a smartphone.

  Recruiting at 4 sites Johns Hopkins University · Baltimore, Maryland and 16 other locations · NCT06986590

• Effects of wild blueberries on heart, brain, and gut health in adults with high blood pressure

  This study tests if eating freeze-dried wild blueberries can improve heart health, brain function, and gut health in adults aged 45-65 with high blood pressure.

  Recruiting Georgia State University · Atlanta, Georgia · NCT06735599

• Improving cardiometabolic and blood pressure health in Detroit through early prevention

  This project will follow adults seen at Wayne Health mobile units who have elevated blood pressure to see if tracking their care, sending text reminders, and offering home monitoring helps improve blood pressure control.

  Recruiting Wayne State University · Detroit, Michigan · NCT06593496

• Egg-derived peptide IRW tested for blood sugar, blood pressure, and weight.

  This project will test whether a small peptide from egg white (IRW), given in a smoothie, can quickly lower blood sugar and blood pressure in adults who have or are at high risk for type 2 diabetes.

  Recruiting Phase 1 University of Alberta · Edmonton, Alberta · NCT06555393

• CardioCare Quest: a co-created game to improve blood pressure medication adherence in Arizona

  This project will test whether a co-designed telehealth game, CardioCare Quest, helps Navajo and other Urban Indigenous adults in Flagstaff better stick to their high blood pressure treatments.

  Recruiting Northern Arizona University · Flagstaff, Arizona and 1 other locations · NCT06487637

• Evaluating Losartan for treating coarctation of the aorta and high blood pressure

  This study is testing if the medication Losartan can help people who have high blood pressure and a heart condition called coarctation of the aorta feel better compared to another medication or a placebo.

  Recruiting Phase 3 Mayo Clinic · Rochester, Minnesota · NCT06150560

• Polypill to prevent heart failure in patients with diabetes

  This study tests if a combination pill can help people with type 2 diabetes who are at high risk for heart failure by improving their heart health and making it easier to stick to their medication.

  Recruiting Phase 1/2 University of Texas Southwestern Medical Center · Dallas, Texas · NCT06143566

• Diagnosing Variable Primary Aldosteronism

  This study is testing if measuring aldosterone levels in urine over 24 hours can help doctors better diagnose people who might have Primary Aldosteronism.

  Recruiting Queen Mary University of London · London · NCT05765786

• Monitoring blood pressure at home for African American teens

  This study is testing if checking blood pressure at home can help find high blood pressure in African American teens more accurately than regular doctor visits.

  Recruiting University Hospitals Cleveland Medical Center · Cleveland, Ohio · NCT05552547

• Comparing Nifedipine and Labetalol for postpartum high blood pressure

  This study is testing whether the medication Nifedipine or Labetalol works better to lower high blood pressure in women after giving birth.

  Recruiting Phase 3 Loma Linda University · Loma Linda, California · NCT05551104

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• What makes high-fat diets raise blood pressure differently in women and men

  A research project explores why eating lots of saturated fat may raise blood pressure more in women than men by studying immune cell changes and fat tissue.

  NIH research Augusta University · Augusta, United States · NIH-11408746

• Cannabis use and heart health in adults with high blood pressure

  A long-term study will follow adults with high blood pressure to see how using cannabis, especially high-THC products, relates to heart health over time.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11360713

• Pharmacist-guided, patient-led blood pressure care for people with kidney disease

  This program helps people with chronic kidney disease work with a clinical pharmacist to manage and adjust their blood pressure medicines at home using a pre-set plan.

  NIH research Iowa City VA Medical Center · Iowa City, United States · NIH-11216512

• Why high‑fat diets raise blood pressure more in women than men

  This project explores how eating a diet high in saturated fat may trigger immune and fat‑tissue changes that raise blood pressure, especially in adult women.

  NIH research Augusta University · Augusta, United States · NIH-11180413

• Understanding Cannabis Use and Heart Health in People with High Blood Pressure

  This project wants to learn how using cannabis might affect the heart health of adults who have high blood pressure.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11128697

• Managing high blood pressure in patients with chronic kidney disease through pharmacist support

  This study is looking at how involving pharmacists can help Veterans with chronic kidney disease better manage their blood pressure by guiding them on how to adjust their medications, so they can feel more in control of their health.

  NIH research Iowa City VA Medical Center · Iowa City, United States · NIH-10942076

• The effects of cannabis use on heart health in patients with high blood pressure

  This study is looking at how using cannabis, especially its main ingredients THC and CBD, might impact heart health in adults who have early-stage high blood pressure, and it's for people who are interested in understanding how their cannabis use could affect their heart.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-10922853

• Understanding why women are more susceptible to high blood pressure from high-fat diets than men

  This study is looking at how eating a high-fat diet affects blood pressure in women differently than in men, and it wants to understand how the immune system plays a part in this, so we can find better ways to help women manage high blood pressure.

  NIH research Augusta University · Augusta, United States · NIH-10918125

• A new approach to managing high blood pressure

  This study is testing a helpful tool called COACH that uses technology and friendly advice to support people with high blood pressure in managing their health better, making it easier for them to stick to lifestyle changes and medication plans.

  NIH research Oregon Health & Science University · Portland, United States · NIH-10872128

Related topics

Quick answers

How many High Blood Pressure clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (11 trials), Ghana (2 trials), Canada (1 trial), Nigeria (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2: 1, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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