The effects of cannabis use on heart health in patients with high blood pressure
Official title: Cannabis use and cardiovascular health outcomes among patients with high blood pressure
Funded at Henry Ford Health + Michigan State University Health Sciences · NIH-10922853 · Data updated 2026-11-12
This study is looking at how using cannabis, especially its main ingredients THC and CBD, might impact heart health in adults who have early-stage high blood pressure, and it's for people who are interested in understanding how their cannabis use could affect their heart.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Henry Ford Health + Michigan State University Health Sciences NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project start | September 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $574,233 |
| NIH project number | 5R01DA057314-02 |
| Project ID | NIH-10922853 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with early-stage high blood pressure.
✕Less likely to help
Patients who do not have high blood pressure or are under 21 years old may not benefit from this research.
What this research studies
This research investigates how cannabis use, particularly its active components THC and CBD, affects cardiovascular health in adults with early-stage high blood pressure. By recruiting patients from primary care clinics in Michigan, the study will collect data through questionnaires, physical exams, and biospecimen analysis over a 30-month period. The goal is to understand the relationship between cannabis use patterns and cardiovascular risk factors, including inflammation and blood vessel function.
Why it matters
Potential benefit: If successful, this research could provide insights into the safety and effects of cannabis use on heart health, potentially guiding treatment options for patients with high blood pressure.
How similar studies have gone: While there is ongoing interest in the effects of cannabis on health, this specific investigation into its impact on cardiovascular outcomes in patients with high blood pressure is relatively novel.
Where this research is happening
-
Henry Ford Health + Michigan State University Health Sciences
East Lansing, United States Active
Researchers
- Principal investigator: Alshaarawy, Omayma O — Henry Ford Health + Michigan State University Health Sciences
- Study coordinator: Alshaarawy, Omayma O
Related research
Other NIH-funded projects on the same topics.
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Cannabis use and heart health in adults with high blood pressure
A long-term study will follow adults with high blood pressure to see how using cannabis, especially high-THC products, relates to heart health over time.
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Understanding Cannabis Use and Heart Health in People with High Blood Pressure
This project wants to learn how using cannabis might affect the heart health of adults who have high blood pressure.
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Hemp-derived CBD for reducing cannabis use in high-THC concentrate users
A randomized, placebo-controlled trial tests whether hemp-derived CBD can help adults who mainly use high-potency cannabis concentrates reduce their cannabis use.
-
Understanding how minority stress affects cannabis use in sexual minorities
A research project follows young adult sexual minorities to see how daily stress and coping help explain cannabis use and related problems.
-
Terminal cannabinoid CB1 receptor changes in schizophrenia and cannabis use
This grant studies how cannabis use and schizophrenia together affect a brain receptor (CB1) and what that could mean for memory and symptoms.
-
Cannabis policies and prenatal cannabis use: how laws affect moms and babies
This grant studies how changes in recreational cannabis laws influence cannabis use during pregnancy and health outcomes for mothers and children.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.